Results 61 to 70 of about 89,060 (300)

P16 expression in human breast carcinoma and its relationship to clinicopathological parameters

Advanced Biomedical Research, 2023
Background: p16 is a cyclin-dependent kinase inhibitor and a cardinal regulator of the cell cycle. The relationship between p16 overexpression and poor prognosis of breast cancer has been reported in some studies.
Fereshteh Mohammadizadeh, Farnaz Nasri
doaj   +1 more source

P16 immunohistochemistry.

, 2014
(A) Presence of HPV as visualized by strong cytoplasmic and nuclear staining for P16 by immunohistochemistry in >70% of the malignant cells. (B) Low P16 staining in
Shankai Yin (142622), Pin Dong (143991), Yanan Xu (678670), Hongliang Yi (491612), Suru Liu (678671), Xiaoyan Li (117291), Jiadong Wang (678672)   +6 more
core   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

P16 ‐ A child with solar urticaria [PDF]

Clinical and Translational Allergy, 2014
Solar urticaria is a rare photodermatosis characterized by pruritus, stinging, erythema, and wheal formation after a brief period of exposure to natural sunlight or an artificial light source emitting the appropriate wavelength. Herein, we present a Turkish boy with solar urticaria.
Yavuz, Suleyman Tolga, Arslan, Mutluay, Uğur Şimşek, Burak   +2 more
openaire   +1 more source

The Application of Liquid-Based Cytological Detection for P16, Cytologic Evaluation and High-Risk Human Papillomavirus Testing in Cervical Cancer Screening: A Clinical Evaluation

, 2022
Fang Zhao,1 Deyong Ma,2 Tingting Wang,3 Yan Zhang,2 Ying Dong,4 Jian Zhao2 1Department of Obstetrics and Gynecology, Beijing Jishuitan Hospital, Beijing, 100035, People’s Republic of China; 2Department of Obstetrics and Gynecology, Peking University ...
Dong Y, Zhang Y, Wang T, Zhao F, Ma D, Zhao J   +5 more
core  

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Loss of P16 in Esophageal Adenocarcinoma Detected by Fluorescence in situ Hybridization and Immunohistochemistry

Acta Medica Bulgarica, 2017
Molecular biology of esophageal adenocarcinoma (EAC) is not fully elucidated. The aim of this study was to assess the expression of cycle regulator and tumor suppressor p16 in esophageal adenocarcinoma. The expression of p16 at protein and gene level was
Kotzev A., Kamenova M.
doaj   +1 more source

Expression of CK7, CK19 and p16 in HPV-mediated oropharyngeal squamous cell carcinoma [PDF]

PeerJ
Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) mediated by human papilloma virus (HPV) has been steadily increasing worldwide.
Qizhang Yan, Pengning Chen, Xinyu Chen, Guanxi Chen, Lin Luo, Ping Ruan, Dahai Yu, Xiaojuan Zeng, Mengyu Zhou   +8 more
doaj   +2 more sources

Relationship between p16 expression and prognosis in different anatomic subsites of OSCC

, 2019
BACKGROUND: p16 has often been found to be overexpressed in patients oral squamous cell carcinoma (OSCC), but its prognostic value between anatomic subsites is still unclear.
Ni, Yanhong, Punyadeera, Chamindie, Wan, Yunxia, Zhang, Xiaoxin, Hu, Qingang, Xiao, Yin, Jing, Yue, Tang, Kai Dun, Huang, Xiaofeng, Song, Yuxian   +9 more
core   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source