Results 71 to 80 of about 210,208 (298)
Role of p16 testing in cervical cancer screening among HIV-infected women.
PLoS ONE, 2017 Backgroundp16 immunohistochemistry is used to evaluate for HPV-associated cervical intraepithelial neoplasia. The diagnostic performance of p16 in HIV infection is unclear.MethodsBetween June-December 2009, HIV-infected women underwent Papanicolaou (Pap)
Christine J McGrath +10 more
doaj +1 more source
Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension. [PDF]
, 2020 Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence-related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset ...
Jabari, Mary +7 more
core
Wave energy potential along the Atlantic coast of Morocco [PDF]
, 2016 This study analyses the wave energy resource along the Atlantic coast of Morocco using a 44-year series of data obtained from numerical modeling (hindcasting). The spatial distribution of wave power is analyzed using data from 23 points along that coast.
Jebbad, Raghda +4 more
core +2 more sources
Hypermethylation of the p16 Gene and Lack of p16 Expression in Hepatoblastoma [PDF]
Modern Pathology, 2003 Hepatoblastoma is the most frequent pediatric liver tumor that develops mostly in young children. Abnormal regulation of cell cycle regulatory genes including p16 has been described, displaying no p16 mRNA and p16 protein in hepatoblastomas. The inactivation of p16, leading to the disruption of cell cycle control is involved in many types of human ...
Yhong-Hee, Shim +7 more
openaire +2 more sources
Advanced Science, EarlyView.This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2006 p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human ...
Emma E. Furth +7 more
doaj +1 more source
A search-based technique for testing from extended finite state machine model [PDF]
, 2009 Extended finite state machines (EFSMs), and languages such as state-charts that are similar to EFSMs, are widely used to model state-based systems. When testing from an EFSM M it is common to aim to produce a set of test sequences (input sequences) that ...
Hierons, RM, Kalaji, AS, Swift, S
core
The Chandra Dust Scattering Halo of Galactic Center transient Swift J174540.7-290015 [PDF]
, 2017 We report the detection of a dust scattering halo around a recently discovered X-ray transient, Swift J174540.7-290015, which in early February of 2016 underwent one of the brightest outbursts (F_X ~ 5e-10 erg/cm^2/s) observed from a compact object in ...
Baganoff, F. +6 more
core +3 more sources
Correlation of p16 Hypermethylation with p16 Protein Loss in Sporadic Gastric Carcinomas [PDF]
Laboratory Investigation, 2000 Hypermethylation of p16 has been detected frequently in a variety of cancer cells and is known to repress the level of p16 transcription. In human gastric carcinoma (GC) cells, p16 protein loss has often been detected, but genetic alterations of p16 are infrequent.
Y H, Shim, G H, Kang, J Y, Ro
openaire +2 more sources
Advanced Science, EarlyView.The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang +8 more
wiley +1 more source