Results 191 to 200 of about 117,126 (251)

Rhythms in longitudinal thalamic recordings are linked to seizure risk

Epilepsia, EarlyView.
Abstract Objective Seizure unpredictability remains a major clinical challenge for people with epilepsy. Previous works have shown that seizure risk is associated with circadian and multi‐day cycles in both brain and physiological signals. However, it remains unclear whether neural activity from deep brain structures such as the anterior nucleus of the
Xinbing Zhang, Zachary T. Sanger, Thomas Lisko, Steffen Ventz, Robert A. McGovern, Theoden I. Netoff   +5 more
wiley   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Perturbation‐induced responses improved seizure forecasting in epileptic rats

Epilepsia, EarlyView.
Abstract Objective The unpredictability of seizures is one of the most challenging aspects of uncontrolled epilepsy for patients. Prior work forecasting seizure risk has measured changes in passive intracranial electroencephalographic (EEG) signals, but currently, there are no such clinical devices available.
Wei‐Chih Chang, Jack Lin, Warwick Cheung, Alan Lai, Mark J. Cook, David B. Grayden, William C. Stacey   +6 more
wiley   +1 more source

Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1

Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1
openaire  

Scavenger receptor CL-P1 mediates endocytosis by associating with AP-2μ2

Scavenger receptor CL-P1 mediates endocytosis by associating with AP-2μ2
openaire  

Some of the next articles are maybe not open access.

Related searches:

Adenosine (P1) receptor signalling

Drug Development Research, 1996
The coupling of the four defined types of adenosine receptors to G proteins and the consequent activation of effector pathways is briefly summarized. It is pointed out that the G proteins are able to influence many types of cellular effector systems, and, in particular, that the a and the β,γ-subunits may activate different signalling pathways that may
Bertil B. Fredholm, Giulia Arslan, Bj�rn Kull, Ewa Kontny, Per Svenningsson   +4 more
openaire   +1 more source

ATP-stimulated ANP release through P1 receptor subtype

Regulatory Peptides, 2005
Extracellular ATP acts as a local regulator of physiological functions in the cardiovascular system via P1 and P2 receptors. However, little is known about the effect of ATP on the release of atrial natriuretic peptide (ANP) secretion. The purpose of this study was to investigate the effects of extracellular ATP on atrial hemodynamics and ANP release ...
Chunhua, Cao, Feng Lian, Piao, Jeong Hee, Han, Sung Zoo, Kim, Suhn Hee, Kim   +4 more
openaire   +2 more sources

Molecular architecture of mouse activating NKR-P1 receptors

Journal of Structural Biology, 2011
Receptors belonging to NKR-P1 family and their specific Clr ligands form an alternative missing self recognition system critical in immunity against tumors and viruses, elimination of tumor cells subjected to genotoxic stress, activation of T cell dependent immune response, and hypertension.
Petr, Kolenko, Daniel, Rozbeský, Ondřej, Vaněk, Vladimír, Kopecký, Kateřina, Hofbauerová, Petr, Novák, Petr, Pompach, Jindřich, Hašek, Tereza, Skálová, Karel, Bezouška, Jan, Dohnálek   +10 more
openaire   +2 more sources

P1- and P2-purine receptors in brain circulation

European Journal of Pharmacology, 1987
As there is increasing evidence that purines are involved in cerebral vasodilatation, purine receptors were characterized pharmacologically in pial arteries from rabbit, cat and man, and compared with purine receptors in various non-cerebral vascular beds.
J E, Hardebo, J, Kåhrström, C, Owman
openaire   +2 more sources

New Heterocyclic Ligands for the Adenosine Receptors P1 and for the ATP Receptors P2

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
BARALDI, Pier Giovanni, ROMAGNOLI, Romeo, AGHAZADEH TABRIZI, Mojgan, BOVERO, Andrea, PRETI, Delia, FRUTTAROLO, Francesca, Moorman AR, BOREA, Pier Andrea   +7 more
openaire   +5 more sources