Results 251 to 260 of about 217,248 (344)

Non‐Synaptic Function and Localization of Syntaxin‐Binding Protein 1 in a Mouse Model of STXBP1‐Related Epileptic Encephalopathy

Annals of Neurology, EarlyView.
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar1, Alexey I. Nesvizhskii, Michael D. Uhler, Jack M. Parent, Yu Wang   +7 more
wiley   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses. [PDF]

J Anim Sci Biotechnol
Chen Y, Ding M, Chen X, Zou T, Liu Y, Chen J, You J.   +6 more
europepmc   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source

Prenatal lipopolysaccharide exposure programs the early-life lung development by modulating mesenchymal fibroblasts in a time- and dose-dependent manner. [PDF]

BMC Med
Dong Y, Hadzic S, Leidner A, Marega M, Procida-Kowalski T, Bartkuhn M, Rivetti S, Ehrhardt H, Bellusci S.   +8 more
europepmc   +1 more source

FDC-P1 myeloid cells engineered to express fibroblast growth factor receptor 1 proliferate and differentiate in the presence of fibroblast growth factor and heparin.

, 1992
M Li, Olivier Bernard
openalex   +2 more sources

Chrysin and Luteolin from Moroccan Propolis to Prevent Aggressive Periodontitis Caused by <i>Aggregatibacter actinomycetemcomitans</i> Leukotoxin: A Computer-Aided Drug Design Approach. [PDF]

Pharmaceuticals (Basel)
El Meskini D, Chraa F, Touhtouh J, Ouadghiri M, Gallo M, Bouyahya A, Aanniz T.   +6 more
europepmc   +1 more source

Ketosis suppression and ageing (KetoSAge): the effect of suppressing ketosis on SHBG and sex hormone profiles in healthy premenopausal women, and its implications for cancer risk and therapy. [PDF]

Front Nutr
Cooper ID, Petagine L, Soto-Mota A, Duraj T, Seyfried TN, Lee DC, Cooper N, Kyriakidou Y.   +7 more
europepmc   +1 more source

Efficacy and Safety of Roflumilast versus Alpha-Lipoic Acid in Type 2 Diabetes with Neuropathy: A Comparative Clinical Study. [PDF]

Diabetes Metab Syndr Obes
Elsharab A, Nooh MZ, Matard RS, Mostafa TM, El-Afify DR.   +4 more
europepmc   +1 more source

Lipopolysaccharide Sensitizes Steroid-Induced Brain Injury in Neonatal Rat Pups. [PDF]

Mediators Inflamm
Chang YS, Yang TM, Hsu YL, Kuo YM, Lin CH.   +4 more
europepmc   +1 more source