Results 151 to 160 of about 398,988 (295)

Dynamic Covalent Radical Recombination for the Assembly of Tuneable Responsive Porous Organic Cages

Angewandte Chemie International Edition, EarlyView.
Dynamic covalent chemistry (DCC) based on reversible radical recombination enables the assembly of responsive, C─C‐linked organic cages. Substituent‐controlled aryldicyanomethyl radicals form discrete, porous architectures with tuneable topology of Tri2 and Tri4 cages, gas selectivity, chromism, and self‐healing behaviour, establishing radical‐based ...
Yannic Hartmann, Robert Oestreich, Yuki Wada, Philippe de Bary, Masaki Kawano, Christoph Janiak, Bernd M. Schmidt   +6 more
wiley   +1 more source

EYA4 promotes cellular senescence by enhancing P21 transcription through interaction with SIX2. [PDF]

Adv Biotechnol (Singap)
Li X, Mao P, Chen D, Li L, Fang H, Huang J, Liu H.   +6 more
europepmc   +1 more source

p21 Knockdown as a Therapeutic Strategy for Focal Cartilage Injury Repair. [PDF]

FASEB J
Larijani L, Ahadzadeh Ardebili A, Ortiz Vales N, Stürmer AT, Krawetz RJ.   +4 more
europepmc   +1 more source

Ontogeny of murine bony semicircular canal form

The Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna, Nathan Jeffery   +1 more
wiley   +1 more source

Quantifying single-cell responses to irradiation in 3D. [PDF]

Front Bioeng Biotechnol
François J, Simerzin A, Jambhekar A, Lahav G.   +3 more
europepmc   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

Cell Type-Specific Expression of p16, p21, and p53 Reveals Age-Dependent Glial Senescence in the App^NL-G-F Mouse Model of Alzheimer's Disease. [PDF]

Aging Cell
Sweeney EM, Abate G, Bakker BRV, Mastinu A, Lai Y, Uberti D, Nilsson P, Tambaro S.   +7 more
europepmc   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

The p21 resilience network: a conceptual framework linking senescence to ferroptosis and cuproptosis resistance. [PDF]

NPJ Syst Biol Appl
Gupta S.
europepmc   +1 more source

A dancing bear, a colleague, or a sharpened toolbox? The cautious adoption of generative artificial intelligence technologies in digital humanities research

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The emergence of generative artificial intelligence (GenAI) is reshaping the research landscape and carries significant implications for Digital Humanities (DH), a field long intertwined with computational methods and technologies. This study examines how DH scholars are adopting and critically evaluating GenAI in their research. Drawing on an
Rongqian Ma, Meredith Dedema, Andrew Cox
wiley   +1 more source