Results 71 to 80 of about 398,988 (295)
Di-san junyi daxue xuebao, 2019 Objective To establish an efficient skin photoaging model in HaCaT cells and investigate the possible signaling pathways of photoaging of skin. Methods After HaCaT cells were exposed to UVB at 30 mJ/cm2, cell proliferation and cell cycle was detected by ...
LIU Chuan +4 more
doaj +1 more source
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Journal of Biomedical Science, 2012 Background Studies have shown the existence of p21 induction in a p53-dependent and -independent pathway. Our previous study indicates that DOX-induced p65 is able to bind the p21 promoter to activate its transactivation in the cells.
Zhou YingQi +5 more
doaj +1 more source
CP Asymmetry in Charged Higgs Decays in MSSM [PDF]
, 2007 We discuss and compare the charge-parity (CP) asymmetry in the charged Higgs boson decays H -> \bar{u}_i d_j for the second and third generation quarks in the minimal supersymmetric standard model.
G. Scharf +7 more
core +2 more sources
Cytoplasmic translocation of p21 mediates NUPR1‐induced chemoresistance [PDF]
FEBS Letters, 2012 The expression of Nuclear Protein 1 (NUPR1) is associated with chemoresistance in multiple malignancies. We previously reported that NUPR1 functions as a transcriptional cofactor for the p300–p53 complex and transcriptionally regulates p21 expression.
Vincent, Andrew J. +6 more
openaire +2 more sources
Self‐Cooling Molecular Spin Qudits
Advanced Materials, EarlyView.A material made of [GdEr] molecular dimers can encode a qudit and perform as a magnetic refrigerant. Microwave resonant pulses coherently manipulate its 16 spin states, while direct demagnetization measurements cool the material and a device down to temperatures below 1 K.
Elías Palacios +12 more
wiley +1 more source
Urology Annals, 2011 Background and Objectives: To evaluate the long-term prognostic value of the combination of the EORTC risk calculator and proapoptotic, antiapoptotic, proliferation, and invasiveness molecular markers in predicting the outcome of intermediate- and high ...
Sultan S Alkhateeb +14 more
doaj +1 more source
Journal of Experimental & Clinical Cancer Research, 2020 Background GLYR1 has a high mutation frequency in microsatellite instability colorectal cancer (MSI CRC) and is presumed to be a novel tumor suppressor. However, the role of GLYR1 in tumors has never been studied.
Zhiyan Hu +8 more
doaj +1 more source
PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth. [PDF]
, 2019 p53 acetylation is indispensable for its transcriptional activity and tumor suppressive function. However, the identity of reader protein(s) for p53 acetylation remains elusive. PBRM1, the second most highly mutated tumor suppressor gene in kidney cancer,
Cai, Weijia +12 more
core +1 more source
Bicomplex Hamiltonian systems in Quantum Mechanics
, 2015 We investigate bicomplex Hamiltonian systems in the framework of an analogous version of the Schrodinger equation. Since in such a setting three different types of conjugates of bicomplex numbers appear, each is found to define in a natural way, a ...
Bagchi, Bijan, Banerjee, Abhijit
core +1 more source