Results 81 to 90 of about 162,345 (168)

Role of lncRNAs in Cellular Aging

Frontiers in Endocrinology, 2016
Aging is a universal, intrinsic and time-dependent biological decay that is linked to intricate cellular processes including cellular senescence, telomere shortening, stem cell exhaustion, mitochondrial dysfunction, and deregulated metabolism.
Lei Sun, Lei Sun, Ufuk Degirmenci, Ufuk Degirmenci   +3 more
doaj   +1 more source

CITED1 promotes proliferation of papillary thyroid cancer cells via the regulation of p21 and p27

Cell & Bioscience, 2018
Background It has been reported that CBP/p300-Interacting Transactivator with glutamic acid [E]/aspartic acid [D]-rich C-terminal domain 1 (CITED1) is overexpressed in papillary thyroid cancer (PTC).
Hai Li, Hongyu Guan, Yan Guo, Weiwei Liang, Liehua Liu, Xiaoying He, Weijian Ke, Xiaopei Cao, Haipeng Xiao, Yanbing Li   +9 more
doaj   +1 more source

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

Journal of Ovarian Research, 2012
Background Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs).
Gallagher Michael F, Heffron Cynthia CBB, Laios Alexandros, O'Toole Sharon A, Ffrench Brendan, Smyth Paul C, Flavin Richard J, Elbaruni Salah A, Spillane Cathy D, Martin Cara M, Sheils Orla M, O'Leary John J   +11 more
doaj   +1 more source

t(3;5)(p21;q32) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on t(3;5)(p21;q32), with data on clinics, and the genes involved.
openaire   +2 more sources

Elucidating the Subcellular Localization of GLRaV-3 Proteins Encoded by the Unique Gene Block in N. benthamiana Suggests Implications on Plant Host Suppression

Biomolecules
Grapevine leafroll-associated virus 3 (GLRaV-3) is a formidable threat to the stability of the global grape and wine industries. It is the primary etiological agent of grapevine leafroll disease (GLD) and significantly impairs vine health, fruit quality,
Patrick Lameront, Mehdi Shabanian, Laura M. J. Currie, Catherine Fust, Caihong Li, Alyssa Clews, Baozhong Meng   +6 more
doaj   +1 more source

The role of p21 in cellular senescence and aging-related diseases

Molecules and Cells
: During the aging process or disease progression, normal cells and tissues in the body undergo various stresses, leading to cell damage and the need for repair, adaptation, apoptosis, or defense responses.
Jiayu Yan, Siyi Chen, Zimei Yi, Ruowen Zhao, Jiayu Zhu, Shuwen Ding, Junhua Wu   +6 more
doaj   +1 more source

Effects of Chronic Intermittent Hypoxia and Subsequent Normoxic Recovery on Renal Senescence and the PI3K/Akt/P21 Pathway in Rats. [PDF]

Int J Nephrol Renovasc Dis
Li H, Chen M, Han F, Zhang H, Jin M, Bai W, Jia C, Han Y, Wei C.   +8 more
europepmc   +1 more source

LincRNA-p21: A Double-Edged Sword in Ethanol-Induced Liver Damage and Its Nanoparticle Solution. [PDF]

Int J Nanomedicine
Wang S, Nie ZC, Liu Y, Zhang ZY, Feng YM, Wang C, Jiang J.   +6 more
europepmc   +1 more source

p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy. [PDF]

Cancer Discov
Zhou L, DeMarco KD, Murphy KC, Wu Z, Li J, Johnson C, Liu B, Giwa HK, Ma B, Bhalerao N, Li J, Jiang Z, Bai S, Parikh CN, Ye T, Simin K, Zhu LJ, Pitarresi JR, Wu H, Ruscetti M.   +19 more
europepmc   +1 more source

Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma. [PDF]

PLoS One
Kubota Y, Kawano M, Itonaga I, Kaku N, Tanaka K.   +4 more
europepmc   +1 more source