Results 121 to 130 of about 204,366 (349)

Bone phenotypes of P2 receptor knockout mice

Frontiers in Bioscience, 2011
The action of extracellular nucleotides is mediated by ionotropic P2X receptors and G-protein coupled P2Y receptors. The human genome contains 7 P2X and 8 P2Y receptor genes. Knockout mice strains are available for most of them. As their phenotypic analysis is progressing, bone abnormalities have been observed in an impressive number of these mice ...
Orriss, Isabel, Syberg, Susanne, Wang, N, Robaye, Bernard, Gartland, Alison, Jorgensen, Niklas, Arnett, Tim, Boeynaems, Jean-Marie   +7 more
openaire   +2 more sources

Purinergic P2 Receptors: Structure and Function 2.0

International Journal of Molecular Sciences, 2023
This Special Issue of the International Journal of Molecular Sciences (IJMS) is a direct continuation of the previous Special Issue of this journal, entitled “Purinergic P2 Receptors: Structure and Function” https://www [...]
openaire   +2 more sources

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Purinergic Signalling in Inflammatory Renal Disease

Frontiers in Physiology, 2013
Extracellular purines have a role in renal physiology and adaption to inflammation. However, inflammatory renal disease may be mediated by extracellular purines, resulting in renal injury.
Nishkantha eArulkumaran, Nishkantha eArulkumaran, Clare eTurner, Marije eSixma, Mervyn eSinger, Robert John Unwin, Frederick WK Tam   +6 more
doaj   +1 more source

P2 Receptor Signaling in Motor Units in Muscular Dystrophy. [PDF]

Int J Mol Sci, 2023
Khairullin AE, Grishin SN, Ziganshin AU.
europepmc   +1 more source

Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies. [PDF]

, 2011
INTRODUCTION: The stroma is the supportive framework of biologic tissue in the breast, consisting of various proteins such as the proteoglycans, decorin and lumican. Altered expression of decorin and lumican is associated with breast tumors.
Ahmed, Shahana, Cerhan, James R, Couch, Fergus J, Dunning, Alison M, Easton, Douglas F, Fredericksen, Zachary S, Goode, Ellen L, Kelemen, Linda E, Pankratz, V Shane, Pharoah, Paul DP, Rider, David N, Scott, Christopher G, Vachon, Celine M, Vierkant, Robert A, Wang, Xianshu   +14 more
core   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Resensitization of TRPV1 channels after the P2 receptor activation in sensory neurons of spinal ganglia in rats. [PDF]

Front Cell Neurosci, 2023
Petrushenko OA, Stratiievska AO, Petrushenko MO, Lukyanetz EA.   +3 more
europepmc   +1 more source

The Effect of N-Terminal Cyclization on the Function of the HIV Entry Inhibitor 5P12-RANTES. [PDF]

, 2017
Despite effective treatment for those living with Human Immunodeficiency Virus (HIV), there are still two million new infections each year. Protein-based HIV entry inhibitors, being highly effective and specific, could be used to protect people from ...
F Nguyen, Anna, J LiWang, Patricia, Jian, Mike, S Schill, Megan   +3 more
core   +2 more sources

Retraction Note: Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells [PDF]

, 2023
Mariachiara Zuccarini, Patricia Giuliani, Silvana Buccella, Valentina Di Liberto, Giuseppa Mudò, Natale Belluardo, Marzia Carluccio, Margherita Rossini, D. F. Condorelli, Michel P. Rathbone, Francesco Caciagli, Renata Ciccarelli, Patrizia Di Iorio   +12 more
openalex   +1 more source