Results 141 to 150 of about 199,121 (304)

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Organic Crystal‐MXene Composites as Temperature‐Tolerant Strain Sensors

Advanced Science, EarlyView.
ABSTRACT Flexible organic crystals offer significant opportunities for organic electronics; however, their potential applications in fields like flexible sensors are at present limited by poor charge transport that result in failure under reversible conditions.
Xuesong Yang, Lijie Wang, Shun Liu, Yuhan Zhang, Yongqiang Xu, Haixia Mei, Liang Li, Ying Tao, Quan‐Hong Yang, Panče Naumov, Hongyu Zhang   +10 more
wiley   +1 more source

Pierceable, Water‐Resistant, and Transparent Nanofilm Electrodes Comprising Carbon Nanotubes for Long‐Term Monitoring of Plant Electrophysiology

Advanced Science, EarlyView.
Ultra‐flexible electrodes composed of single‐walled carbon nanotubes on a polymeric substrate exhibit excellent transparency, water resistance, and conformability to hairy surfaces. These non‐invasive nanofilms are easily pierced by trichomes, overcoming the structural barriers in plant electrophysiology.
Yusuke Hori, Tatsuhiro Horii, Shinji Masuda, Toshinori Fujie   +3 more
wiley   +1 more source

Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?

Journal of Innate Immunity
Background: Interstitial lung diseases (ILD) are poorly understood disorders characterised by diffuse damage to the lung parenchyma, with inflammation and fibrosis.
Luke Forde, Debananda Gogoi, Rory Baird, Cormac McCarthy, Michael P. Keane, Emer P. Reeves, Emmet E. McGrath   +6 more
doaj   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

Prevention of P2 Receptor-Dependent Thrombocyte Activation by Pore-Forming Bacterial Toxins Improves Outcome in A Murine Model of Urosepsis. [PDF]

Int J Mol Sci, 2020
Christensen MG, Johnsen N, Skals M, Hamilton ADM, Rubak P, Hvas AM, Praetorius H.   +6 more
europepmc   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Covalent Bonds Reinforced Strength and Modulus of Heterocyclic Aramid Fiber by Interfacial Aminated‐MXene Nanosheets

Advanced Science, EarlyView.
We demonstrate the covalent bonds strategy to enhance the mechanical property of PBIA fiber by using interfacial MXene‐NH2 nanosheets. The MXene‐NH2 nanosheets with reactive amino sites that can serve as nucleating agents and chain anchors to enhance orientation, crystallinity and interchain interaction of PBIA fiber via strong interfacial amido ...
Boyuan Chen, Hansheng Liu, Weiheng Kong, Ke Han, Jing Fang, Xingjiang Wu, Jianhong Xu, Hao Li   +7 more
wiley   +1 more source

Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P2 Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance. [PDF]

Front Physiol, 2020
Cruz AM, Beall C.
europepmc   +1 more source