Results 1 to 10 of about 99,821 (298)

Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells.

, 1995
The macrophage colony-stimulating factor (M-CSF) regulates proliferation and differentiation of cells belonging to the monocytic lineage. We have investigated the nature and origin of the proliferation and differentiation signals derived from the M-CSF ...
Rohrschneider, L. R., Chen, A. R., Myles, G. M., Carlberg, K., Bourette, R. P.   +4 more
core   +2 more sources

Involvement of purinergic signalling in the vasomotor response to hypochlorous acid in porcine coronary artery

Hypochlorous acid (HOCl) is generated by neutrophils during the innate immune response. ATP is released from cells by various stimuli and during inflammation but whether ATP is released by and participates in the response to HOCl is unclear.
Dunn, William R, Ralevic, Vera, Baghdadi, Ashwaq   +2 more
core   +1 more source

Development of a Novel Fiber Optic Sensor Combined with a Fluorescence Turn-on Probe for Cu (II) Detection

E3S Web of Conferences, 2013
Existing staining-based methodology for the detection of metal ions is not well suited for real-time or in situ use. This is a significant problem, given that these ions can have a considerable impact on both human health and the environment. Thus, there
Ma J., Chiniforooshan Y., Hao W. H., Bock W.J., Wang Z. Y., Dabek-Zlotorzynska E.   +5 more
doaj   +1 more source

Abstract P1-11-05: Phase 2 Study of Neoadjuvant Treatment with Cellular Redox Modulator NOV-002 in Combination with Doxorubicin and Cyclophosphamide Followed by Docetaxel (AC→T) in Patients with Stage II-III HER-2 (-) Breast Cancer

, 2010
Background: NOV-002 (a formulation of disodium glutathione disulfide) modulates signaling pathways involved in tumor cell proliferation and metastasis and enhances anti-tumor immune responsiveness in tumor models.
Avisar, E, Pegram, M, Vogel, C L, Hermann, V, F Moffat, S. Gluck, Baker, M K, Rodgers, S, V Hermann, S Rodgers, Welsh, C F, CL Vogel, DJ Cole, MK Baker, J Hurley, CJ Pazoles, Slingerland, J, M Pegram, P Seo, Hurley, J, Seo, P, CM Diaz, CF Welsh, AJ Montero, Koniaris, L, E Garrett-Mayer, K Schuhwerk, Garrett-Mayer, E, Cole, D J, Schuhwerk, K, Moffat, F, Diaz, C M, J Slingerland, E Avisar, Montero, A J, Gluck, S, O Silva, Pazoles, C J, Silva, O, L Koniaris   +39 more
core   +1 more source

Mutational analysis of the P1 phosphorylation domain in escherichia coli CheA, the signaling kinase for chemotaxis

, 2016
The histidine autokinase CheA functions as the central processing unit in the Escherichia coli chemotaxis signaling machinery. CheA receives autophosphorylation control inputs from chemoreceptors and in turn regulates the flux of signaling phosphates to ...
Nishiyama, So-ichiro, Garzón, Andrés, Parkinson, John S.   +2 more
core   +1 more source

Case report: CAR-T therapy demonstrated safety and efficacy in relapsed/refractory diffuse large B-cell lymphoma patients complicated with hepatitis B-related cirrhosis

Frontiers in Oncology
Chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated both efficacy and safety in relapsed/refractory diffuse large B-cell lymphoma (DLBCL) patients infected with hepatitis B virus (HBV).
Danqing Kong, Danqing Kong, Nana Ping, Nana Ping, Qian Zhu, Qian Zhu, Xiao Zhang, Xiao Zhang, Junhong Li, Junhong Li, Rui Zou, Depei Wu, Depei Wu, Zhengming Jin, Zhengming Jin, Changju Qu, Changju Qu   +16 more
doaj   +1 more source

Expression of corticotrophin-releasing hormone receptor subtypes in human myometrium and cloning of the promoter region for the CRH receptors type 2 [PDF]

Corticotrophin releasing hormone (CRH) and CRH receptor (CRH-R) appear to play a number of important roles in human pregnancy. The purpose of the first part of my project was to clone and sequence CRH-R subtypes from human myometrial biopsies.
Chen, Jing
core  

Pharmacological and Molecular Characterisation of P2Y Receptors in Endothelial and Epithelial Cells [PDF]

, 2007
Submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyIn light of the significant modulation of receptor activity previously shown by a peptide (designated L247), designed to mimic ...
D’Souza, Vijay Kenneth
core  

Expression and tissue localization of collectin placenta 1 (CL-P1, SRCL) in human tissues

, 2008
Udgivelsesdato: JuneCollectin placenta-1 (CL-P1), also known as scavenger receptor with C-type lectin (SRCL), is a type II membrane glycoprotein that shares structural features with both collectins and type A scavenger receptors.
Sellman, Lana, Hansen, Søren, Skjødt, Karsten, Holmskov, Uffe, Nielsen, Ole, Floridon, Charlotte   +5 more
core   +1 more source

Attenuated mRNA expression of inflammatory mediators in neonatal rat lung following lipopolysaccharide treatment

Journal of Inflammation Research, 2012
Valerie Le Rouzic, Kari Wiedinger, Heping ZhouDepartment of Biological Sciences, Seton Hall University, South Orange, NJ, USAAbstract: Neonates are known to exhibit increased susceptibility to bacterial and viral infections and increasing evidence ...
Zhou H, Wiedinger K, Le Rouzic V
doaj