Results 11 to 20 of about 99,821 (298)

Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse

Nature Communications, 2022
Signaling by the human C-type lectin-like receptor, natural killer (NK) cell inhibitory receptor NKR-P1, has a critical role in many immune-related diseases and cancer.
Kalousková, Barbora; orcid:, Skořepa, Ondřej; orcid:, Vaněk, Ondřej; orcid:, Harlos, Karl, Dušková, Jarmila, Stránský, Jan; orcid:, Dohnálek, Jan; orcid:, Abreu, Celeste, Hašek, Jindřich; orcid:, Kovaľ, Tomáš; orcid:, Bláha, Jan; orcid:, Pazicky, Samuel; orcid:, Zhao, Yuguang, Skálová, Tereza; orcid:, Cmunt, Denis; orcid:, Poláchová, Edita; orcid:, Grobárová, Valéria; orcid:   +16 more
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Systematic analyses of the sequence conservation and ligand interaction patterns of purinergic P1 and P2Y receptors provide a structural basis for receptor selectivity

Computational and Structural Biotechnology Journal, 2023
Purinergic receptors are membrane proteins that regulate numerous cellular functions by catalyzing reactions involving purine nucleotides or nucleosides.
Yoon, Hongryul, Jiho Yoo, Ri Han, Han, Ri, Hongryul Yoon, Yoonji Lee, Lee, Yoonji, Yoo, Jiho   +7 more
core   +2 more sources

Nuclear Respiratory Factor 1 Negatively Regulates the P1 Promoter of the Peroxisome Proliferator-Activated Receptor-γ Gene and Inhibits Chicken Adipogenesis [PDF]

Frontiers in Physiology, 2018
Peroxisome proliferator-activated receptor-γ (PPARγ) is a master regulator of adipogenesis, and alterations in its function are associated with various pathological processes related to metabolic syndrome.
Tianyu Xing, Yankai Chu, Fang Mu, Xin You, Tingting Cui, Yanfei Jin, Jiaxin Huang, Hui Li, Ning Wang   +8 more
core   +3 more sources

P1 receptors and cytokine secretion [PDF]

Purinergic Signalling, 2007
Evidence has accumulated in the last three decades to suggest tissue protection and regeneration by adenosine in multiple different cell types. Adenosine produced in hypoxic or inflamed environments reduces tissue injury and promotes repair by receptor ...
Stefania Ceruti, S. Ceruti, M.P. Abbracchio, Maria P. Abbracchio   +3 more
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Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama

Biomedicines, 2021
The human ErbB3 receptor confers resistance to the pharmacological inhibition of EGFR and HER2 receptor tyrosine kinases in cancer, which makes it an important therapeutic target.
Valeria M. Ukrainskaya, Nickolay A. Knyazev, Olga V. Shamova, Anna D. Mikushina, Stanislav V. Shmakov, Anastasiya I. Afremova, Viktoria M. Ekimova, Anna A. Vronskaia, Anna N. Yudenko, Igor E. Eliseev   +9 more
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ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Receptor Activation by ATP Through Rapid and Localized Generation of Adenosine by Ecto-nucleotidases

Journal of Pharmacological Sciences, 2004
Extracellular ATP is now recognized as a neurotransmitter or neuromodilator in the nervous system, producing diverse physiological effects by activating multiple P2 receptors.
Satoko Ohkubo, Isao Matsuoka
core   +2 more sources

Hepatitis C virus E1 protein-specific linear B-cell epitopes, pan-genotype reactivity, and functional relevance. [PDF]

Front Immunol
BackgroundHepatitis C virus (HCV) infection poses a major global risk for chronic liver disease, underscoring the critical need for prevention. Our previous studies demonstrated that HCV-modified soluble E1/E2F442NYT envelope glycoproteins delivered from
Preedia BE, Haga Y, Ray R.
europepmc   +2 more sources

Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011
CC-BY-NC-NDBACKGROUND: Scavenger receptors are generally expressed in macrophages and vascular endothelial cells and some scavenger receptors are thought to contribute to the development of atherosclerosis. METHODS: We cloned the cDNA of a zebrafish CL-
ワカミヤ, ノブタカ, 森, 健一郎, 本村, 亘, ヨシダ, イツロウ, Mori, Ken-ichiro, Yoshida, Itsuro, Ohtani, Katsuki, Jang, Seong-Jae, 高後, 裕, Wakamiya, Nobutaka, 大谷, 克城, Fukuda, Mitsuko, コウゴ, ユタカ, スズキ, ヤスヒコ, ヨシザキ, タカユキ, 吉田, 逸朗, オオタニ, カツキ, フクダ, ミツコ, Yoshizaki, Takayuki, Kohgo, Yutaka, 福田, 光子, モトムラ, ワタル, 若宮, 伸隆, Motomura, Wataru, モリ, ケンイチロウ, 吉崎, 隆之, 鈴木, 定彦, Suzuki, Yasuhiko   +27 more
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The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells [PDF]

Journal of Biological Chemistry, 2001
American Society for Biochemistry and Molecular Biology, Katsuki, Ohtani ; Yasuhiko, Suzuki ; Souji, Eda ; Takao, Kawai ; Tetsuo, Kase ; Hiroyuki, Keshi ; Yoshinori, Sakai ; Atsushi, Fukuoh ; Takashi, Sakamoto ; Hiroyuki, Itabe ; Tatsuo, Suzutani ...
Kase, T, Yoshida, I, オオタニ, カツキ, Suzuki, Y, Keshi, H, Suzutani, T, Eda, S, Ogasawara, M, Sakamoto, T, Ohtani, Katsuki, Wakamiya, N, Fukuoh, A, Itabe, H, 大谷, 克城, Kawai, T, Sakai, Y   +15 more
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Molecular Characterisation of NKR-P1 receptor in peripheral blood of Pig [PDF]

Veterinary World, 2008
Characterization of natural killer receptor-p1 (NKR-P1) in the leukocytes from peripheral blood of pig revealed three different clones of NKR-P1, 1,2 and 3. The RT-PCR product of human NKR-P1 gene was 573 base pair (bp). The RT-PCR product of pig NKR-P1 gene was 661bp. [Veterinary World 2008; 1(7.000): 197-200]
Banshi Sharma, Marc Goaverts, Prof. Bruno Godderris   +2 more
openaire   +1 more source