Results 31 to 40 of about 117,126 (251)
Frontiers in Physiology, 2018 Peroxisome proliferator-activated receptor-γ (PPARγ) is a master regulator of adipogenesis, and alterations in its function are associated with various pathological processes related to metabolic syndrome.
Tingting Cui +27 more
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Purinergic Regulation of Food and Fat Intakes in Broiler’s Central Nervous System [PDF]
Iranian Journal of Veterinary Medicine, 2021 BACKGROUND: Adenosine has many physiological roles in the brain, and in rodents, it changes food intake when applied centrally. OBJECTIVES: We investigated the effect of central injection of the purine molecule adenosine on both food and fat intakes in ...
Sahel Motaghi +3 more
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P1-508 Oestrogen receptor β expression in colorectal cancer [PDF]
Journal of Epidemiology and Community Health, 2011 Introduction The oestrogen receptor β (ERβ) is the primarily expressed ER in the large intestine and has been found to have inhibitory effects on colon cancer cells. We therefore investigated, whether the ERβ expression in tumour tissue from colorectal cancer (CRC) patients is associated with tumour/clinical ...
A Rudolph +7 more
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Frontiers in Cellular Neuroscience, 2019 Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary ...
Robert J. Reklow +13 more
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Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate. [PDF]
PLoS ONE, 2014 Diadenosine tetraphosphate (Ap4A), a constituent of platelet dense granules, and its P1,P4-dithio and/or P2,P3-chloromethylene analogs, inhibit adenosine diphosphate (ADP)-induced platelet aggregation. We recently reported that these compounds antagonize
Hung Chang +8 more
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The aberrant expression of the mesenchymal variant of FGFR2 in the epithelial context inhibits autophagy [PDF]
, 2019 Signaling of the epithelial splice variant of fibroblast growth factor receptor 2 (FGFR2b) triggers both differentiation and autophagy, while the aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells induces impaired differentiation ...
Belleudi, Francesca +4 more
core +1 more source
Variation in the Thyrotropic Activity of Human Chorionic Gonadotropin in Chinese Hamster Ovary Cells Arises from Differential Expression of the Human Thyrotropin Receptor and Microheterogeneity of the Hormone. [PDF]
, 1995 The role of hCG as a stimulator of the human thyroid has been a subject of controversy, because discrepant results have been obtained in different in vitro assays.
Amir, S.M. +4 more
core +1 more source
Purinergic Signalling: Therapeutic Developments
Frontiers in Pharmacology, 2017 Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted until the early 1990’s when receptor subtypes for purines and pyrimidines were cloned and ...
Geoffrey Burnstock, Geoffrey Burnstock
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Virus Research, 2022 The H9N2 subtype of influenza A virus circulates frequently among poultry in Asian and North African countries causing economic loss in the poultry sector. The antigenic variations of the H9N2 virus were at the origin of its genetic evolution through the
Marwa Arbi +7 more
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Медицинская иммунология, 2020 Physical and chemical factors, obesity, lipid metabolism disorder, diabetes affect the state of the vascular endothelium, the processes of thrombus formation, fibrinolysis and increase the risk of developing cardiovascular diseases.
L. B. Masnavieva +2 more
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