Results 41 to 50 of about 99,821 (298)

Purinergic Regulation of Food and Fat Intakes in Broiler’s Central Nervous System [PDF]

Iranian Journal of Veterinary Medicine, 2021
BACKGROUND: Adenosine has many physiological roles in the brain, and in rodents, it changes food intake when applied centrally. OBJECTIVES: We investigated the effect of central injection of the purine molecule adenosine on both food and fat intakes in ...
Sahel Motaghi, Hossein Jonaidi, Alireza Bashiri, Samaneh Nouri Gooshki   +3 more
doaj   +1 more source

NK and T cells constitute two major, functionally distinct intestinal epithelial lymphocyte subsets in the chicken [PDF]

, 2001
Non-mammalian NK cells have not been characterized in detail; however, their analysis is essential for the understanding of the NK cell receptor phylogeny.
Manfred Stangassinger, Göbel, Thomas W. F., Stangassinger, Manfred, Kaspers, Bernd, Thomas W. F. Göbel, Bernd Kaspers   +5 more
core   +1 more source

Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate. [PDF]

PLoS ONE, 2014
Diadenosine tetraphosphate (Ap4A), a constituent of platelet dense granules, and its P1,P4-dithio and/or P2,P3-chloromethylene analogs, inhibit adenosine diphosphate (ADP)-induced platelet aggregation. We recently reported that these compounds antagonize
Hung Chang, Ivan B Yanachkov, Edward J Dix, Milka Yanachkova, Youfu Li, Marc R Barnard, George E Wright, Alan D Michelson, Andrew L Frelinger   +8 more
doaj   +1 more source

Towards a revised nomenclature for P1 and P2 receptors

Trends in Pharmacological Sciences, 1997
8
B. Fredholm, M. Abbracchio, G. Burnstock, G. Dubyak, T. Harden, K. Jacobson, U. Schwabe, M. Williams   +7 more
openaire   +3 more sources

Purinergic Signalling: Therapeutic Developments

Frontiers in Pharmacology, 2017
Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted until the early 1990’s when receptor subtypes for purines and pyrimidines were cloned and ...
Geoffrey Burnstock, Geoffrey Burnstock
doaj   +1 more source

Inhibition of avian influenza virus H9N2 infection by antiviral hexapeptides that target viral attachment to epithelial cells

Virus Research, 2022
The H9N2 subtype of influenza A virus circulates frequently among poultry in Asian and North African countries causing economic loss in the poultry sector. The antigenic variations of the H9N2 virus were at the origin of its genetic evolution through the
Marwa Arbi, Imen Larbi, Jihen Nsiri, Imen El Behi, Ahmed Rejeb, Khaled Miled, Adeljelil Ghram, Mehdi Houimel   +7 more
doaj   +1 more source

Abstract P1-18-13: Efficacy and safety of palbociclib plus endocrine therapy in Black and Hispanic patients with hormone receptor positive/human epidermal growth factor receptor 2-negative advanced breast cancer (HR+/HER2- ABC) participating in the PALOMA trials

, 2022
Background: The PALOMA clinical trials have shown that palbociclib (PAL) plus endocrine therapy (ET) is a safe and effective treatment for HR+/HER2- ABC.
Theall, Kathy Puyana, Isaacs, Claudine, Lynce, Filipa, Rugo, Hope S., Bananis, Eustratios, Mahtani, Reshma, Kalmadi, Sujith, Castrellon, Aurelio, Huang, Xin, Sleckman, Bethany   +9 more
core   +1 more source

Adenosine and P1 receptors: Key targets in the regulation of sleep, torpor, and hibernation

Frontiers in Pharmacology, 2023
Graphical AbstractAdenosine mediates sleep, torpor and hibernation through P1 receptors. Recent reasearch has shown that P1 receptors play a vital role in the regulation of sleep-wake, torpor and hibernation-like states. In this review, we focus on the roles and neurobiological mechanisms of the CNS adenosine and P1 receptors in these three states ...
Wei-Xiang Ma, Ping-Chuan Yuan, Hui Zhang, Ling-Xi Kong, Michael Lazarus, Wei-Min Qu, Yi-Qun Wang, Zhi-Li Huang   +7 more
openaire   +3 more sources

Autoantibody as markers of the heart state in patients with vibration disease burdened diabetes mellitus

Медицинская иммунология, 2020
Physical and chemical factors, obesity, lipid metabolism disorder, diabetes affect the state of the vascular endothelium, the processes of thrombus formation, fibrinolysis and increase the risk of developing cardiovascular diseases.
L. B. Masnavieva, I. V. Kudaeva, Yu. A. Kuznetsova   +2 more
doaj   +1 more source

BACL is a novel brain-associated, non-NKC-encoded mammalian C-type lectin-like receptor of the CLEC2 family

, 2013
Natural Killer Gene Complex (NKC)–encoded C-type lectin-like receptors (CTLRs) are expressed on various immune cells including T cells, NK cells and myeloid cells and thereby contribute to the orchestration of cellular immune responses.
Mittelbronn, Michel Guy André, Michel Mittelbronn, Olga Lysenko (420632), Alexander Steinle (254716), Schulte, Dorothea, Lysenko, Olga, Dorothea Schulte, Steinle, Alexander, Alexander Steinle, Dorothea Schulte (420633), Olga Lysenko, Michel Mittelbronn (307400)   +11 more
core   +1 more source