Results 191 to 200 of about 199,121 (304)

A dancing bear, a colleague, or a sharpened toolbox? The cautious adoption of generative artificial intelligence technologies in digital humanities research

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The emergence of generative artificial intelligence (GenAI) is reshaping the research landscape and carries significant implications for Digital Humanities (DH), a field long intertwined with computational methods and technologies. This study examines how DH scholars are adopting and critically evaluating GenAI in their research. Drawing on an
Rongqian Ma, Meredith Dedema, Andrew Cox
wiley   +1 more source

From disorientation to preparedness: Information practices as scaffolding in acute crises

Journal of the Association for Information Science and Technology, EarlyView.
Abstract This qualitative study examines how adults in Israel enacted information practices during an acute national crisis. Using the information transitions framework, we investigate how concrete practices emerge and evolve across three stages: understanding, negotiating, and resolving. Semi‐structured Zoom interviews with 18 adults were analyzed via
Lilach Alon, Tali Malinoff, Inbar Levkovich   +2 more
wiley   +1 more source

Autistic Children With Speech Onset Delay Show Reversed Bias in Spectral Versus Temporal Auditory Processing

Autism Research, EarlyView.
ABSTRACT A recent “hierarchical” reinterpretation of the neurological basis of autism suggests that in autism with early language delay, perceptual processing may be favored over the integration of transmodal information. This model is largely based on neuroimaging findings relating to visual processing, but predicts a corresponding reorganization in ...
Luodi Yu, Shuyu Xie, Li Wang, Laurent Mottron   +3 more
wiley   +1 more source

ATP-related purinergic signaling via P2Y12 contributes to airway epithelial barrier integrity. [PDF]

BMC Mol Cell Biol
Tsuya K, Maruoka S, Okamoto S, Shikano S, Ujike M, Yamada S, Kurosawa Y, Mizumura K, Kozu Y, Gon Y.   +9 more
europepmc   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Distinct phosphoinositide signatures orchestrate FcεRI versus MRGPRX2 mast cell secretion. [PDF]

iScience
Omari-Manaa S, Aharonov R, Galli SJ, Ali H, Sagi-Eisenberg R.   +4 more
europepmc   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Influence of Peptide-Based Chelator Sequences on HER2-Targeting Radiopeptide. [PDF]

J Pept Sci
Gupta S, Kumar M, Repaka KM, Das A, Kengar AA, Satpati D.   +5 more
europepmc   +1 more source

Listening to Hong Kong children's perspectives through pretend play

British Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley   +1 more source

‘A completely different space’: Teachers' perspectives on disadvantage, access to nature and outdoor learning

British Educational Research Journal, EarlyView.
Abstract This study examined teachers' perspectives on how children benefit from time in nature, how disadvantage shapes access and the role of schools in facilitating such access. Drawing on interviews conducted in 2022 with 25 UK primary school teachers who participated in Generation Wild, a nature connection programme for schools in economically ...
Nicola Parkin, Kersty Hobson, Wouter Poortinga, Mark Stead, Julia Newth, Jonathan Reeves, Merideth Gattis   +6 more
wiley   +1 more source