Results 211 to 220 of about 204,366 (349)
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
P2 Receptor Excitation of Rodent Hypoglossal Motoneuron ActivityIn VitroandIn Vivo: A Molecular Physiological Analysis [PDF]
, 1997 Gregory D. Funk +6 more
openalex +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Roles of P2 receptors in glial cells: focus on astrocytes [PDF]
, 2006 Maria P. Abbracchio, Stefania Ceruti
openalex +1 more source
Reconfigurable Acoustofluidic Microvortices for Selective Microcargo Delivery
Advanced Science, EarlyView.This work introduces a frequency‐encoded, reconfigurable acoustofluidic system that overcomes the low throughput and poor selectivity of conventional micro‐delivery methods. By exploiting discrete microbubble resonances to program adaptive microvortex modes, the platform enables real‐time switching and selective guidance of microscale payloads through ...
Lei Wang +6 more
wiley +1 more source
How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?
Advanced Science, EarlyView.This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen +5 more
wiley +1 more source
Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells [PDF]
, 2008 Dong Reoyl Seo +8 more
openalex +1 more source