Results 241 to 250 of about 199,121 (304)

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Role of Nucleotide P2 Receptors in the Immune System: Focus on Effector T Cells. [PDF]

Cells
Babou Kammoe RB, Hamoudi C, Aoudjit F.
europepmc   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

Developmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee, Ebenezer N. Yamoah, Jennifer Kersigo, Karen Elliott, Niya LaRoda, Gabriela Pavlinkova, Bernd Fritzsch   +6 more
wiley   +1 more source

Comparative study of cardio-protective effect of metformin versus dapagliflozin in experimentally induced myocardial infarction in diabetic rats. [PDF]

BMC Pharmacol Toxicol
Elhantery D, Mokbel SA, Hussein AM, Tayee EM, Desouky SE, Taha AM.   +5 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium. [PDF]

Stem Cell Res Ther
Jia W, Yan H, Huang J, Liu W, Fu Z, Tian D, Xu W, Chen X, Gao Y, Yu H.   +9 more
europepmc   +1 more source

Purinergic Receptors in Dendritic Cells. [PDF]

J Inflamm Res
Wang M, Zhao X, Hou S, Wu Z, Yin HY.
europepmc   +1 more source

Lipids regulate epidermal growth factor receptor activation by its ligands. [PDF]

Biochem Soc Trans
Hutchison JM, Lemmon MA.
europepmc   +1 more source

Single-Cell Transcriptomic Analysis of Macaque LGN Neurons Reveals Novel Subpopulations. [PDF]

Mol Neurobiol
Sun SH, Renshaw KT, Pezaris JS.
europepmc   +1 more source

Immune checkpoints in a genetically engineered mouse model of spontaneous autoimmune uveitis. [PDF]

J Immunol
Yin M, Hiam-Galvez KJ, Proekt I, Chan J, Hu Y, Lowell CA, Caspi RR, Spitzer MH, Anderson MS, DeFranco AL.   +9 more
europepmc   +1 more source