Results 281 to 290 of about 92,291 (308)

The discovery and development of P2 receptor subtypes

Journal of the Autonomic Nervous System, 2000
Extracellular purine and pyrimidine nucleotides modulate cellular activity by acting at P2 receptors. The first receptor to be identified was the P(2)-purinoceptor, which was characterised and named in 1978. In the 1980s this site was subdivided into P(2X) and P(2Y) purinoceptors on the basis of pharmacological criteria in functional studies on native ...
openaire   +2 more sources

Subtypes of P2 Receptors in Rat Neuromuscular Junction

Bulletin of Experimental Biology and Medicine
At the neuromuscular junction, ATP and its metabolite adenosine regulate the release of acetylcholine by activating purinergic receptors (P2), thereby regulating the function of skeletal muscles under normal and pathological conditions. The presence of P2 receptors in the neuromuscular junction was assessed immunohistochemically on sections of m ...
A E, Khairullin, A N, Khabibrakhmanov, D V, Efimova, D V, Samigullin, S N, Grishin, M A, Mukhamedyarov, A U, Ziganshin   +6 more
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Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Özge Gümüsay, Damé Idossa   +2 more
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Boll, Sandrine Valadè   +2 more
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul H Parikh, Sagar Lonial
exaly  

Agonists and antagonists for P2 receptors.

Novartis Foundation symposium, 2006
Recent work has identified nucleotide agonists selective for P2Y1, P2Y2 and P2Y6 receptors and nucleotide antagonists selective for P2Y1, P2Y12 and P2X1 receptors. Selective non-nucleotide antagonists have been reported for P2Y1, P2Y2, P2Y6, P2Y12, P2Y13, P2X(2/3)/P2X3 and P2X7 receptors.
Kenneth A, Jacobson, Stefano, Costanzi, Bhalchandra V, Joshi, Pedro, Besada, Dae Hong, Shin, Hyojin, Ko, Andrei A, Ivanov, Liaman, Mamedova   +7 more
openaire   +1 more source

P1 and P2 Receptors in Platelets

2001
Because of the importance of platelets in haemostasis and thrombosis, these cell fragments have been extensively studied for many years and the existence of receptors for adenosine and adenine nucleotides on platelets has been recognised since the early 1960s.
openaire   +1 more source

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

Nature Reviews Drug Discovery, 2011
Uwe Rudolph, Frédéric Knoflach, Rudolph Uwe   +2 more
exaly  

Development of subtype-selective oestrogen receptor-based therapeutics

Nature Reviews Drug Discovery, 2011
Jan-Ake Gustafsson, Nilsson Stefan, Gustafsson Jan-Ake   +2 more
exaly  

Targeting pathological B cell receptor signalling in lymphoid malignancies

Nature Reviews Drug Discovery, 2013
Ryan M Young, Louis M Staudt, Young Ryan M   +2 more
exaly