Results 201 to 210 of about 135,603 (303)

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Communication between Corneal Epithelial Cells and Trigeminal Neurons Is Facilitated by Purinergic (P2) and Glutamatergic Receptors

, 2012
Duane Oswald, Albert Lee, Monique Trinidad, Cheryl Chi, Ruiyi Ren, Celeste B. Rich, Vickery Trinkaus‐Randall   +6 more
openalex   +2 more sources

The German Research Unit “Neuronal and glial P2 receptors; molecular basis and functional significance” [PDF]

, 2010
Torsten Schöneberg, Péter Illés, Geoffrey Burnstock   +2 more
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Extracellular Nucleotides and P2 Receptors in Renal Function.

Physiol Rev, 2020
Vallon V, Unwin R, Inscho EW, Leipziger J, Kishore BK.   +4 more
europepmc   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself

, 2015
Cian M. McCrudden, Martin O’Rourke, Kim E. Cherry, Hiu-Fung Yuen, Declan O’Rourke, Muhammad Babur, Brian A. Telfer, Huw D. Thomas, Patrick F. Keane, Thiagarajan Nambirajan, Chris Hagan, Joe M. O’Sullivan, Chris Shaw, Kaye J. Williams, Nicola J. Curtin, David G. Hirst, Tracy Robson   +16 more
openalex   +2 more sources

P2 Receptor Excitation of Rodent Hypoglossal Motoneuron ActivityIn VitroandIn Vivo: A Molecular Physiological Analysis [PDF]

, 1997
Gregory D. Funk, Refik Kanjhan, Carmen Walsh, Janusz Lipski, Alison M. Comer, Marjorie A. Parkis, Gary D. Housley   +6 more
openalex   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Roles of P2 receptors in glial cells: focus on astrocytes [PDF]

, 2006
Maria P. Abbracchio, Stefania Ceruti
openalex   +1 more source