Results 191 to 200 of about 60,226 (246)

Restoring oscillatory dynamics in Alzheimer's disease: A laminar whole-brain model of serotonergic psychedelic effects. [PDF]

Netw Neurosci
Gendra JC, Lopez-Sola E, Castaldo F, Lleal-Custey È, Sanchez-Todo R, Vohryzek J, Salvador R, Andrzejak RG, Ruffini G, Alzheimer’s Disease Neuroimaging Initiative.   +9 more
europepmc   +1 more source

Purinergic signaling and cholangiocyte regeneration: a new frontier in ischemic liver injury. [PDF]

Front Transplant
Nwaduru C, Anyagwa OE, Fenlon M, Buff M, Selim M, Botha J, Kastenberg Z, Zimmerman M.   +7 more
europepmc   +1 more source

A Prolonged Norovirus Infection and the Molecular Evolution of Human Norovirus Within-Host in a Child with Burkitt Lymphoma. [PDF]

Viruses
Jia L, De R, Li Z, Han Z, Liu L, Dong H, Feng S, Liu R, Zhao L.   +8 more
europepmc   +1 more source

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell-Selective Bioactivity. [PDF]

Macromol Biosci
Cosimi A, Pollehn R, De Martino A, Manzke S, Kerkhoff Y, Nickl P, Lohmann T, Keshi E, Lee-Thedieck C, Weinhart M.   +9 more
europepmc   +1 more source

A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain. [PDF]

Cell
Brann DH, Tsukahara T, Tau C, Kalloor D, Lubash R, Kannan LT, Klimpert N, Kollo M, Escamilla-Del-Arenal M, Bintu B, Schaefer A, Fleischmann A, Bozza T, Datta SR.   +13 more
europepmc   +1 more source

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Ocular P2 receptors and glaucoma

Neuropharmacology, 2023
Adenosine triphosphate (ATP), an energy source currency in cells, is released or leaked to the extracellular space under both physiological and pathological conditions. Extracellular ATP functions as an intercellular signaling molecule through activation of purinergic P2 receptors.
Youichi, Shinozaki, Kozo, Saito, Kenji, Kashiwagi, Schuichi, Koizumi   +3 more
openaire   +2 more sources

P2 receptors in the kidney

Journal of the Autonomic Nervous System, 2000
Our understanding of the actions of extracellular ATP in controlling kidney function via stimulation of P2 receptors is still at an early stage. Recently, several groups, including our own, have begun to address this subject: in this brief review, we discuss some of these effects and speculate on likely function of extracellular nucleotides in the ...
M A, Bailey, K A, Hillman, R J, Unwin
openaire   +2 more sources

P2 receptors and cancer

Trends in Pharmacological Sciences, 2006
Purinergic signalling has been implicated in many biological processes, and ATP and other extracellular nucleotides might have therapeutic potential in the treatment of cancer by signalling through P2 receptors. Different P2 receptor subtypes have been identified in a variety of different cancer types, in both primary samples of human cancer tissue and
Nicholas, White, Geoffrey, Burnstock
openaire   +2 more sources

Overview of the P2 Receptors

Seminars in Thrombosis and Hemostasis, 2005
The release of nucleotides in extracellular fluids can result from cell necrosis, exocytosis of secretory granules (such as platelet dense granules), or efflux through membrane channels. In addition, recent evidence suggests that vesicular trafficking is an important pathway of nucleotide release.
Boeynaems, Jean-Marie, Communi, Didier, Suarez Gonzalez, Nathalie, Robaye, Bernard   +3 more
openaire   +3 more sources

P2 receptors: intracellular signaling

Pflügers Archiv - European Journal of Physiology, 2006
P2 receptors for extracellular nucleotides are divided into two categories: the ion channel receptors (P2X) and the G-protein-coupled receptors (P2Y). For the P2X receptors, signal transduction appears to be relatively simple. Upon activation by extracellular ATP, a channel comprised of P2X receptor subunits opens and allows cations to move across the ...
Laurie, Erb, Zhongji, Liao, Cheikh I, Seye, Gary A, Weisman   +3 more
openaire   +2 more sources