Results 21 to 30 of about 135,603 (303)
Comprehensive insights into potential roles of purinergic P2 receptors on diseases: Signaling pathways involved and potential therapeutics. [PDF]
J Adv ResGuo Y +9 more
europepmc +2 more sources
A Purinergic P2 Receptor Family-Mediated Increase in Thrombospondin-1 Bolsters Synaptic Density and Epileptic Seizure Activity in the Amygdala-Kindling Rat Model [PDF]
Frontiers in Cellular Neuroscience, 2018 Previous studies suggested that the thrombospondin-1/transforming growth factor-β1 (TSP-1/TGF-β1) pathway might be critical in synaptogenesis during development and that the purinergic P2 receptor family could regulate synaptogenesis by modulating TSP-1 ...
Hongliu Sun +9 more
doaj +2 more sources
P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages. [PDF]
Int J Mol Sci, 2020 Zhang Y +4 more
europepmc +3 more sources
Purinergic Receptors in Dendritic Cells [PDF]
Journal of Inflammation ResearchMiaomiao Wang,1 Xiaoxiao Zhao,1 Shuai Hou,1 Zhongbo Wu,2 Hai-yan Yin1 1School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Brain Disease Research Center, Tongren People’s ...
Wang M, Zhao X, Hou S, Wu Z, Yin HY
doaj +2 more sources
Purinergic P2 Receptors: Structure and Function 2.0. [PDF]
Int J Mol Sci, 2023 This Special Issue of the International Journal of Molecular Sciences (IJMS) is a direct continuation of the previous Special Issue of this journal, entitled “Purinergic P2 Receptors: Structure and Function” https://www [...]
Zemkova H.
europepmc +3 more sources
Physiologic roles of P2 receptors in leukocytes. [PDF]
J Leukoc Biol, 2022 AbstractSince their discovery in the 1970s, purinergic receptors have been shown to play key roles in a wide variety of biologic systems and cell types. In the immune system, purinergic receptors participate in innate immunity and in the modulation of the adaptive immune response. In particular, P2 receptors, which respond to extracellular nucleotides,
Alberto AVP +10 more
europepmc +3 more sources
Molecular recognition in P2 nucleotide receptors [PDF]
Nucleic Acids Symposium Series, 2003 Kenneth A. Jacobson
openalex +3 more sources
Alzheimer and Purinergic Signaling: Just a Matter of Inflammation?
Cells, 2021 Alzheimer’s disease (AD) is a widespread neurodegenerative pathology responsible for about 70% of all cases of dementia. Adenosine is an endogenous nucleoside that affects neurodegeneration by activating four membrane G protein-coupled receptor subtypes,
Stefania Merighi +5 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall +5 more
doaj +1 more source
Microbes Infect, 2012 Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on multiple immune cell responses such as T lymphocyte proliferation, chemotaxis, cytokine release ...
Rayah A +2 more
europepmc +4 more sources