Results 31 to 40 of about 21,110 (244)
Biochemistry of P2y-purinergic receptors.
Japanese Journal of Pharmacology, 1990 T. Kendall Harden
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P2X1 receptors and the endothelium
Memorias do Instituto Oswaldo Cruz, 2005 Adenosine triphosphate (ATP) is now established as a principle vaso-active mediator in the vasculature. Its actions on arteries are complex, and are mediated by the P2X and P2Y receptor families.
LS Harrington, JA Mitchell
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Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium
Cell Communication and Signaling, 2005 Background It was previously shown that K+ secretion by strial marginal cell epithelium is under the control of G-protein coupled receptors of the P2Y family in the apical membrane.
Scofield Margaret A +5 more
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P2Y receptors and pain transmission [PDF]
Purinergic Signalling, 2004 It is widely accepted that the most important ATP receptors involved in pain transmission belong to the P2X(3) and P2X(2/3) subtypes, selectively expressed in small diameter dorsal root ganglion (DRG) neurons. However, several types of the metabotropic ATP (P2Y) receptors have also been found in primary afferent neurons; P2Y(1) and P2Y(2) receptors are
Gerevich, Zoltan, Illes, Peter
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Scientific Reports, 2017 Purinergic P2Y 2 receptors, G-protein coupled receptors that primarily couple with Gαq/11-proteins, are activated equipotently by adenosine-5′-triphosphate (ATP) and uridine-5′-triphosphate.
Kensuke Sakuma +4 more
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The relationship between P2X4 and P2X7: a physiologically important interaction? [PDF]
, 2013 Purinergic signaling within the kidney is becoming an important focus in the study of renal health and disease. The effectors of ATP signaling, the P2Y and P2X receptors, are expressed to varying extents in and along the nephron.
Birch, Rebecca E +3 more
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Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
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Differential inhibitory effects of CysLT(1) receptor antagonists on P2Y(6) receptor-mediated signaling and ion transport in human bronchial epithelia. [PDF]
PLoS ONE, 2011 BACKGROUND: Cysteinyl leukotriene (CysLT) is one of the proinflammatory mediators released by the bronchi during inflammation. CysLTs exert their biological effects via specific G-protein-coupled receptors. CysLT(1) receptor antagonists are available for
Wendy Ka-hoi Lau +3 more
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Purinergic Signaling in Liver Pathophysiology
Frontiers in Endocrinology, 2021 Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP.
Shanu Jain, Kenneth A. Jacobson
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Purinergic receptor mediated calcium signalling in urothelial cells [PDF]
, 2019 Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M +4 more
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