ANKRA2 interacts with p35 and is a substrate for Cdk5/p35
Cdk5 is a serine/threonine kinase that plays a pivotal role in neural development. Activation of Cdk5 requires its association with its activator, p35 or p39. More than forty proteins have been identified as the substrates for Cdk5.
Ng, Kung Yau
core
Early diagnosis of Gastric adenocarcinoma could increase survival of the patients and also remarkably reduce treatment costs. This study aimed at evaluating the diagnostic value of serum P35 in comparison with tissue P35 in gastric adenocarcinoma and their relationship with microscopic prognostic factors.
Amir, Vahedi +5 more
openaire +1 more source
Involvement of Cdk5/p35 in EphB2-dependent dendritic spine development
Dendritic spines are small protrusions from dendrites, whose morphological changes are thought to play important roles in synaptic plasticity. Recent studies have revealed multiple signaling pathways that regulate dendritic spine development, among which
Wu, Qian
core
Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescence. [PDF]
Hashikawa K +18 more
europepmc +1 more source
New Pathological Insights into Biomarkers for Multimodal Therapeutic Approach in Hepatic Neuroendocrine Tumors: A Detailed Case Report. [PDF]
Tsai YC, Lin CH, Hung CH, Ou JJ, Lee YT.
europepmc +1 more source
Postnatal Development of Pyramidal Neurons Excitability and Synaptic Inputs in Mouse Gustatory Cortical Circuits. [PDF]
Schiff H, Maffei A.
europepmc +1 more source
Increased Osteoclast Activity Contributes to Bone Resorption and Osteopenia in a Rett Syndrome Mouse Model. [PDF]
Samee N +5 more
europepmc +1 more source
The Recycling Endosomal (Na<sup>+</sup>, K<sup>+</sup>)/H<sup>+</sup> Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin-Dependent Kinase 5 to the Plasma Membrane. [PDF]
Flessner R +6 more
europepmc +1 more source
P35 The combined gold assessment, muscle weakness and walking distance: Abstract P35 Table 1. [PDF]
JM Seymour +4 more
openaire +1 more source
Functional investigation of the neuronal Cdk5 activator p35 in the regulation of actin dynamics
Cdk5 is a unique member of the cyclin-dependent kinase (Cdk) family of proline-directed Ser/Thr protein kinases. In conjunction with its neuron-specific activator p35, Cdk5 plays an essential role in the development of the central nervous system.
Yu, Yan
core

