Results 101 to 110 of about 25,694 (216)
Drebrin is phosphorylated by Cdk5-p35 in cultured cells.
, 2014 GFP-tagged drebrin E (A) or A (B) was transfected with Cdk5-p35 or kinase-negative (kn) Cdk5-p35 in Neuro2A cells. Cells were harvested 24 h after transfection and the cell lysates were subjected to Laemmli’s (upper panels) or Phos-tag SDS-PAGE (lower ...
Junya Takahashi (538349) +12 more
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Cdk5/p35 can form a complex with DRD2.
, 2013 (A) GST pull-down assay using purified recombinant GST-D2i3 protein with rat brain extract. GST pull-down precipitates were subjected to Western blotting analyses. ‘Bead’ indicates the pull-down precipitate without GST proteins.
Yongdo Kwak (306080) +10 more
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Exposing the specific roles of the invariant chain isoforms in shaping the MHC class II peptidome
Frontiers in Immunology, 2013 The peptide repertoire (peptidome) associated with MHC class II molecules (MHCIIs) is influenced by the polymorphic nature of the peptide binding groove but also by cell-intrinsic factors.
Jean-Simon eFortin +2 more
doaj +1 more source
Intracellular localization of the p35 subunit of murine IL-12
, 2003 Production of interleukin-12 (IL-12), a heterodimer of p35 and p40 subunits, is limited by p35 expression. A long and a short murine p35 mRNA potentially encoding proteins differing in pre-sequence size are produced.
Schwartzbach, Steven D. +3 more
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Regulation of neuronal axon specification by glia-neuron gap junctions in C. elegans
eLife, 2016 Axon specification is a critical step in neuronal development, and the function of glial cells in this process is not fully understood. Here, we show that C.
Lingfeng Meng +3 more
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The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein
, 2010 The neuronal Cdk5 activator p35 is involved in a multitude of neuronal activities, including cytoskeletal organization. We show here that p35 directly interacts with filamentous actin (F-actin) but not with monomeric actin (G-actin). Through binding, p35
Qi, Robert Z. +11 more
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Effect of p35 mutations on axon elongation and neuronal migration.
, 2015 (A) Mouse brain cortical neurons in culture were transfected with p35, wt, A108V or L302I, with EGFP using Lipofectoamine 2000 at 0 DIV. Axons were observed with EGFP and measured at 3 DIV, using Zen software associated with confocal microscopy ...
Shunsuke Takada (338027) +5 more
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Baculoviral p35 inhibits oxidant-induced activation of mitochondrial apoptotic pathway
, 2003 In this study we report that the baculovirus p35 anti-apoptotic protein prevents cell death by quenching free radicals at a very upstream step in the apoptotic pathway. Mitochondria of activated rat peritoneal macrophages as well as Spodoptera frugiperda
Hasnain, Seyed E. +6 more
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Expression of baculovirus P35 prevents cell death in Drosophila [PDF]
, 1994 The baculovirus P35 protein functions to prevent apoptotic death of infected cells. We have expressed P35 in the developing embryo and eye of the fly Drosophila melanogaster. P35 eliminates most, if not all, normally occurring cell death in these tissues,
Hay, Bruce A. +2 more
core
Calmodulin binding and Cdk5 phosphorylation of p35 regulate its effect on microtubules
, 2008 In the nervous system, Cdk5 and its neuronal activator p35 are involved in the control of various activities, including neuronal differentiation and migration.
Qi, Robert Z., Hou, Zhibo, He, Lisheng
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