Results 91 to 100 of about 25,694 (216)

‘Being an Outsider’ and ‘Being an Insider’: A Focused Ethnography of Family Members' Visitation Experiences in an Adult ICU

Journal of Advanced Nursing, Volume 82, Issue 7, Page 7441-7452, July 2026.
ABSTRACT Aims To explore how the restricted visitation policy impacts family members' visitation experiences and perceptions in an adult intensive care unit (ICU). Design Focused ethnography. Methods Data collection included 39 observation sessions (totalling 65.3 h), 19 semi‐structured interviews with family members, and document analysis of policies ...
Lian Zhu, Susanne Kean, Catherine Clarissa, Jennifer Tocher   +3 more
wiley   +1 more source

“I'm Not Here to Teach You How to Be Gay:” LGBTQ+ Client Experiences of Othering in Emotionally Focused Couple Therapy

Journal of Marital and Family Therapy, Volume 52, Issue 3, July 2026.
ABSTRACT Despite the increasing emphasis on addressing the intersections of client and therapist identity to improve therapeutic outcomes, therapy clients holding marginalized identities continue to experience othering. Othering is a process that engenders marginalization and inequality based on preconceived group identity, involves the hegemonic ...
Caitlin Edwards, Lekie Dwanyen, Andrea Wittenborn, Robert Allan   +3 more
wiley   +1 more source

The protein SET binds the neuronal Cdk5 activator p35(nck5a) and modulates Cdk5/p35(nck5a) activity

, 2002
The neuronal Cdk5 kinase is composed of the catalytic subunit Cdk5 and the activator protein p35(nck5a) or its isoform, p39(nck5ai). To identify novel p35(nck5a)- and p39(nck5ai)-binding proteins, fragments of p35(nck5a) and p39(nck5ai) were utilized in ...
Q Li (6964538), NS Cheung (14539535), D Qu (13296009), JH Wang (7938038), R Li (660811), RZ Qi (15885572), H-Y Lim (13638175)   +6 more
core  

Degradation and cleavage of p35 and its mutants.

, 2015
(A) Expression of p35 in COS-7 cells. Wild-type p35 (wt) or its mutants, p35 A108V:L178L (A108V) and p35 L302I, were expressed alone (–) or together with wild-type (wt) CDK5 or kinase-negative (kn) CDK5 D144N in COS-7 cells.
Shunsuke Takada (338027), Taro Saito (358910), Karl Peter Giese (814072), Keiko Mizuno (814071), Akiko Asada (538347), Shin-ichi Hisanaga (177755)   +5 more
core   +1 more source

Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez, Daniela Jiménez‐Díaz, Rafael Esteve‐Pérez, Alexandru Vasile‐Tudorache, Jordan E. Read, Sasha R. Howard, Carmen Agustín‐Pavón   +6 more
wiley   +1 more source

Polyphosphates Attenuate Interleukin‐12 Production in Macrophages Infected With Legionella pneumophila

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew, Archana Jayaraman, Johannes Platten, Shuang Xu, Sarah Josinsky, Julian Roewe, Maximilian Mimmler, Jonathan Kilroy, Fedoua Echahidi, Ziya Kaya, Dario S. Zamboni, Christoph Reinhardt, Markus Bosmann   +12 more
wiley   +1 more source

Dependence of p35 nuclear export on its NES.

, 2014
(A) Consensus sequence of the NES on p35. The functional NES comprises a core of closely spaced leucine residues or other hydrophobic amino acids. The critical hydrophobic residues in the putative NES of p35 are underlined.
Winnie W. Y. Chien (645660), Wing-Yu Fu (645659), Xiao-su Zhao (386365), Amy K. Y. Fu (645661), Zhen Li (49109), Nancy Y. Ip (255933)   +5 more
core   +1 more source

Peripheral and orofacial pain sensation is unaffected by the loss of p39

Molecular Pain, 2017
Cdk5 is a key neuronal kinase necessary for proper brain development, which has recently been implicated in modulating nociception. Conditional deletion of Cdk5 in pain-sensing neurons attenuates pain responses to heat in both the periphery and orofacial
Michaela Prochazkova, Bradford Hall, Minghan Hu, Tracy Okine, Jennifer Reukauf, BK Binukumar, Niranjana D Amin, Eva Roque, Harish C Pant, Ashok B Kulkarni   +9 more
doaj   +1 more source

Colocalization of p35 with AATYK1A in early and recycling endosomes.

, 2013
(A) Colocalization of AATYK1A and p35 in COS-7 cells. COS-7 cells were transfected with AATYK1A-Myc together with p35 and Cdk5. AATYK1A and p35 were detected by immunostaining with the anti-Myc antibody and anti-p35 antibody, followed by incubation with ...
Koji Tsutsumi (365453), Shin-ichi Hisanaga (177755), Tetsuya Takano (365454), Ryo Endo (365455), Mitsunori Fukuda (87862), Mineko Tomomura (365456), Toshio Ohshima (154229)   +6 more
core   +1 more source

Nonsurgical Hand Rejuvenation With Dermicol-P35 30G [PDF]

Aesthetic Surgery Journal, 2009
Aesthetic hand rejuvenation and restoration have been relatively overlooked compared with other aesthetic enhancements. Cosmetic dermal fillers provide physicians and patients with a nonsurgical option for restoring volume and a youthful appearance to the aging and damaged hand.
openaire   +2 more sources