Results 81 to 90 of about 25,694 (216)
The Journal of Physiology, EarlyView.Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba +8 more
wiley +1 more source
SNPs located in human p35 and amino acid differences between human and other mammalian p35 forms.
, 2015 Amino acid exchanges reported as SNPs for human p35 or for other mammalian p35 forms. A108A and L302L are indicated by a box. The p25 and CDK5-activation domains are indicated above the molecule.
Shunsuke Takada (338027) +5 more
core +1 more source
Cdk5 activation promotes Cos-7 cells transition towards neuronal-like cells
Translational Neuroscience, 2023 Cyclin-dependent kinase 5 (Cdk5) activity is specifically active in neurogenesis, and Cdk5 and neocortical neurons migration related biomarker are expressed in Cos-7 cells.
Bao Li +11 more
doaj +1 more source
Glia, Volume 74, Issue 8, August 2026.Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales +9 more
wiley +1 more source
Native Chemical Ligation in Covalent Caspase Inhibition by p35
, 2006 SummaryWide-spectrum caspase inhibition by the baculoviral p35 protein was previously shown to be a consequence of covalent inhibition in which a thioester bond is stably formed between the cleavage residue Asp87 of p35 and the active site Cys360′ of ...
David Eliezer +7 more
core +1 more source
Annals of Neurology, Volume 100, Issue 1, Page 154-170, July 2026.Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Ethics &Human Research, Volume 48, Issue 4, Page 6-19, July–August 2026.ABSTRACT It is important to know what motivates people, especially from groups underrepresented in biomedical research, to accept or decline participation in research studies. With this information, engagement strategies, incentives to participate, and benefits of participation can be aligned with what potential research participants value and expect ...
Carolyn P. Neuhaus +3 more
wiley +1 more source
p35 regulates NIF-1 subcellular localization.
, 2014 (A) Nuclear localization of NIF-1 in COS-7 cells. HA-tagged NIF-1 expressing COS-7 cells were stained with HA and NIF-1 antibody. The nuclei were stained with DAPI.
Winnie W. Y. Chien (645660) +5 more
core +1 more source
Cloning, Expression and Characterization of Toxoplasma gondii P35 protein in E. coli [PDF]
Cell Journal, 2006 Introduction: Toxoplasma gondii is a protozoan parasite which is globallyprevalent in human and animals. Toxoplasma infection is commonlyasymptomatic, but can cause serious medical problems inimmunocompromised individuals and in fetus.
Parviz Kavakeb +2 more
doaj
The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
MedComm, Volume 7, Issue 7, July 2026.Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source