Results 211 to 220 of about 76,399 (242)
Some of the next articles are maybe not open access.
ANKRA2 interacts with p35 and is a substrate for Cdk5/p35
2014Cdk5 is a serine/threonine kinase that plays a pivotal role in neural development. Activation of Cdk5 requires its association with its activator, p35 or p39. More than forty proteins have been identified as the substrates for Cdk5. By phosphorylating these diverse cellular targets, Cdk5 plays a multifunctional role in nervous system including neurite ...
openaire +2 more sources
Peripeti
Peripeti 35 © Peripeti og forfatterne Temaredaktion Solveig Gade, Johan Holm Mortensen, Storm Møller Madsen, Anika Marschall, Thomas Rosen dal Nielsen. Redaktion Janicke Branth, Erik Exe Christoffersen, Solveig Daugaard, Michael Eigtved, Solveig Gade, Falk Heinrich, Storm Møller Madsen, Johan Holm Mortensen, Thomas Rosendal Nielsen (ansv ...
openaire +1 more source
Peripeti 35 © Peripeti og forfatterne Temaredaktion Solveig Gade, Johan Holm Mortensen, Storm Møller Madsen, Anika Marschall, Thomas Rosen dal Nielsen. Redaktion Janicke Branth, Erik Exe Christoffersen, Solveig Daugaard, Michael Eigtved, Solveig Gade, Falk Heinrich, Storm Møller Madsen, Johan Holm Mortensen, Thomas Rosendal Nielsen (ansv ...
openaire +1 more source
Molecular Brain Research, 2002
Cyclin-dependent kinase 5 (cdk5) is involved in the development of the nervous system and neuronal process outgrowth, and it regulates several intracellular processes including cytoskeletal dynamics. Dysregulation of cdk5 has been implicated in many disorders of the nervous system.
Petri, Kerokoski +4 more
openaire +2 more sources
Cyclin-dependent kinase 5 (cdk5) is involved in the development of the nervous system and neuronal process outgrowth, and it regulates several intracellular processes including cytoskeletal dynamics. Dysregulation of cdk5 has been implicated in many disorders of the nervous system.
Petri, Kerokoski +4 more
openaire +2 more sources
Activity and regulation of p35 / Cdk5 kinase complex
2000Publisher Summary This chapter discusses the activity and regulation of p35/Cdk5 kinase complex. The importance of the p35/Cdk5 kinase in cortical development has been shown by mouse knockout experiments. In neurons, both p35 and Cdk5 localize to the actin-rich peripheral lamellipodia of growing axons.
M, Nikolic, L H, Tsai
openaire +2 more sources
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
Nature, 1999G. Patrick +5 more
semanticscholar +1 more source
Cdk5/p35 Regulates Neuronal Migration
2008Neurons migrate from proliferative zone to their final position during brain development. Cyclin-dependent kinase 5 (Cdk5) plays an important role in neuronal migration to establish a proper structure of the brain.
openaire +1 more source

