Results 171 to 180 of about 166,874 (259)

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Statement of Retraction: Nesfatin-1 protects against diabetic cardiomyopathy in the streptozotocin-induced diabetic mouse model via the p38-MAPK pathway. [PDF]

Bioengineered
europepmc   +1 more source

Effects of Electroacupuncture on Knee Osteoarthritis in Rats Through Suppressing p38 MAPK/ERK/CREB Pathway. [PDF]

J Inflamm Res
Wang J, Wang F, Guo Y, Liu T, Li J, Zou J, Luan F, Gao T, Wang W.   +8 more
europepmc   +1 more source

Trends in functions and inhibitors of p38

Folia Pharmacologica Japonica, 2015
openaire   +3 more sources

Anchors or relational risks? Educator and psychologist narratives of attachment in child–robot relationships

British Journal of Educational Psychology, EarlyView.
Abstract Background As AI‐enabled social robots become more common in schools, children may form strong emotional bonds with them despite robots not being caregivers and lacking the capacities for “true” attachment. Given limited understanding of potential risks and safeguards, professional perspectives are needed to inform responsible design and ...
Dimitris Pnevmatikos, Panagiota Christodoulou   +1 more
wiley   +1 more source

Neuroprotectin D1 regulating the inflammation and nerve restoration in <i>Aspergillus fumigatus</i> keratitis. [PDF]

Int J Ophthalmol
Li H, Jia YY, Wu MQ, Zhang LN, Lin J, Wang Q, Li C, Zhao GQ.   +7 more
europepmc   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

TMEM72 Inhibits the proliferation by promoting cellular senescence through the activation of the P38/MAPK signaling pathway in renal cell carcinoma. [PDF]

Transl Oncol
Dai F, Wang H, Chu W, Lin Y, He J, Wen H, Feng X, Liu X, Xu Z, Bi L, Lyu Z.   +10 more
europepmc   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, EarlyView.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

ADAM15 promotes the progression and metastasis of hepatocellular carcinoma by activating the JNK/p38 pathway. [PDF]

Sci Rep
Junhui X, Mengyun S.
europepmc   +1 more source