Results 191 to 200 of about 281,509 (352)

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Microenvironmental Cues That Regulate Cancer Cell Dormancy in Estrogen-Receptor Positive and Triple-Negative Breast Cancer Cell Lines. [PDF]

Cancer Med
Maniar J, Datt P, Dange PP, Kailaje V, Lakhera M, Samarth M, Durve T, Kadam A, Gandhi KA, Gupta S.   +9 more
europepmc   +1 more source

Phenotype‐guided etiologic workup in a prospective cohort of 144 adults with developmental and epileptic encephalopathy

Epilepsia Open, EarlyView.
Abstract Objectives Adults with developmental and epileptic encephalopathies (DEEs) often enter adult neurology care without etiologic clarification because of incomplete transition from pediatric services, outdated investigations, and attenuation of childhood electro‐clinical features over time.
Giuseppe d’Orsi, Umberto Costantino, Maria Teresa Di Claudio, Carmela Pia Ferro, Pietro Palumbo, Mario Benvenuto, Massimiliano Copetti, Leonardo D'Agruma, Massimo Carella, Marco Castori, Orazio Palumbo   +10 more
wiley   +1 more source

Effective-Component Compatibility of Bufei Yishen Formula Alleviates Alveolar Epithelial Barrier Damage in COPD Through Inhibition of p38 MAPK Phosphorylation. [PDF]

Int J Chron Obstruct Pulmon Dis
Shao X, Zhang L, Guo M, Wang C, Chu H, Mo Y, Lu R, Zhao P, Tian Y.   +8 more
europepmc   +1 more source

Seismic Performance and Vibration‐Based Damage Identification of Two‐Storey Balloon‐Framed CLT Shear Walls

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT While cross‐laminated timber (CLT) is increasingly utilized in lateral force‐resisting systems in mass timber construction, research has predominantly focused on platform‐type construction. Balloon‐type CLT shear wall systems offer distinct structural advantages, notably the elimination of cumulative perpendicular‐to‐grain compression and a ...
Samira Mohammadyzadeh, Houman Ganjali, Jianhui Zhou, Thomas Tannert   +3 more
wiley   +1 more source

Bioactive Lipid Mediator Resolvin D5 Suppresses Melanogenesis in α-MSH-Stimulated B16F10 Cells via ROS-Associated p38/β-Catenin/MITF Regulation. [PDF]

J Microbiol Biotechnol
Choi HJ, Park SJ, Choi JW, Im GE, Lee H, Choi S, Oh DK, Shin KC, Jeong JB.   +8 more
europepmc   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation. [PDF]

J Cell Mol Med
Qian C, Gu Y, Gao F, Xu Z, Li J, Liu S, He R, Zhong L, Wang J.   +8 more
europepmc   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

Peripheral Sympathetic Sprouting Drives Neuropathic Pain via Spinal Microglial P2Y12 Activation in a Rat Spinal Nerve Ligation Model. [PDF]

J Pain Res
Yu T, Huang H, Li Z, Yan H.
europepmc   +1 more source