Results 251 to 260 of about 327,693 (283)
PTPRK promotes resiniferatoxin-induced postherpetic neuralgia via activating DUSP1/p38 MAPK signaling pathway in dorsal root ganglia. [PDF]
Zhao Y +5 more
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Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells. [PDF]
Wang X +6 more
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Microglia-derived neuroinflammatory pathways in neuropathic pain. [PDF]
Pu W +5 more
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Artesunate preserves post-resuscitation myocardial and neurologic function in a rat model of cardiac arrest and cardiopulmonary resuscitation. [PDF]
Li H +8 more
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YK-4-279 Induces Osteosarcoma Cell Cycle Arrest, DNA Damage Response, and Apoptosis by Regulating the MAPK Cascade. [PDF]
Wang W, Zhang Y, Jia X, Han L, Xin M.
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Benzimidazolone p38 inhibitors
Bioorganic & Medicinal Chemistry Letters, 2004The synthesis and in vitro p38 alpha activity of a novel series of benzimidazolone inhibitors is described. The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors ...
Mark A, Dombroski +17 more
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