Results 161 to 170 of about 205,636 (290)

Protective Effects of Potential Probiotic Pediococcus acidilactici 100 Against Multi‐Drug‐Resistant Diarrheal Escherichia coli Strains Induced Changes in Caenorhabditis elegans Model System

open access: yesFood Safety and Health, EarlyView.
This study shows the protective effects of potential probiotic strain of Pediococci strains against diarrheal Escherichia coli strains in Caenorhabditis elegans model system. The E. coli strains resulted in severe morphological and physiological damage to the worm whereas the probiotic interventions were able to reduce these damages.
Gunjan Sadera   +4 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

open access: yesiMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu   +6 more
wiley   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang   +3 more
wiley   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

open access: yesiMetaOmics, EarlyView.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu   +14 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

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