Results 251 to 260 of about 229,819 (298)

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Targeting p38 MAPK signaling pathway:  Quercetin as a novel therapy for TMJ synovitis. [PDF]

Int J Mol Med
Cheng M, Guan Y, Xin X, Yi X, Liu Y.
europepmc   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

TRPC6 governs brown adipose thermogenesis via a BMPR2-p38 MAPK signaling axis. [PDF]

Mol Metab
Xie D, Peng Y, Zhang S, Mai X, Wen W, Wang M, Wang QP, Sun J.   +7 more
europepmc   +1 more source

Pachymic Acid Alleviates Non-Alcoholic Fatty Liver Disease via FGF21-Mediated Inhibition of the p38 MAPK Pathway. [PDF]

Food Sci Nutr
Nie L, Ma D, Deng X, Erbu A, Wang F, Shi W, Li Z, Cui H, Wen W.   +8 more
europepmc   +1 more source

Hepatocyte CD146 and soluble CD146 promote hepatic stellate cell activation via the integrin αvβ1-p38 MAPK signaling axis to drive liver fibrosis. [PDF]

Cell Mol Life Sci
Yang B, Hou C, Ye R, Yin J, Shu Y, Cheng X, Sun L, Yang K, Sun Q, Li Y, Xie W, Wang Q, Wang Q.   +12 more
europepmc   +1 more source

Osteocytes regulate osteoprotegerin expression via the p38-MAPK-CREB pathway in rheumatoid arthritis. [PDF]

JBMR Plus
Yasumoto K, Fujiwara T, Sugita T, Arisumi S, Kawamura S, Utsunomiya T, Hara D, Kawahara S, Yamaguchi R, Akasaki Y, Hamai S, Motomura G, Yamada H, Nakashima Y.   +13 more
europepmc   +1 more source

Obeticholic acid attenuates complete freund's adjuvant-induced arthritis in rats through FXR-mediated modulation of TGF-β/TAK1/MKK3/p38 MAPK signaling, inflammation, and oxidative stress. [PDF]

Inflammopharmacology
Senna MM, Shiha NA, Zaki HF, Ramadan LAA, Mustafa AM.   +4 more
europepmc   +1 more source

P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts. [PDF]

Aging (Albany NY)
Zhu S, Zhou JQ, Wang K, Guo ML, Sanders YY.   +4 more
europepmc   +1 more source