Results 71 to 80 of about 205,636 (290)

Correlation between p38 mitogen-activated protein kinase and human telomerase reverse transcriptase in sarcomas

Journal of Experimental & Clinical Cancer Research, 2012
Background One of the major components of telomerase is the human telomerase reverse transcriptase (hTERT) as the catalytic protein. hTERT mRNA expression are reported to be associated with prognosis and tumor progression in several sarcomas.
Matsuo Toshihiro, Shimose Shoji, Kubo Tadahiko, Fujimori Jun, Yasunaga Yuji, Sugita Takashi, Ochi Mitsuo   +6 more
doaj   +1 more source

Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population [PDF]

, 2016
The identification of signaling pathways that affect the cancer stem-like phenotype may provide insights into therapeutic targets for combating embryonal rhabdomyosarcoma.
Ciccarelli, Carmela, DI PAOLO, Virginia, Giampaolo, Adele, Gravina, GIOVANNI LUCA, Hassan, Hamisa Jane, Macioce, Giampiero, Marampon, Francesco, Milazzo, Luisa, Tombolini, Vincenzo, Vulcano, Francesca, Zani, Bianca Maria   +10 more
core   +9 more sources

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

Nuclear Localization of p38 MAPK in Response to DNA Damage

International Journal of Biological Sciences, 2009
p38 MAP kinase (MAPK) is activated in response to environmental stress, cytokines and DNA damage, and mediates death, cell differentiation and cell cycle checkpoints.
C. David Wood, Tina M. Thornton, Guadalupe Sabio, Roger A. Davis, Mercedes Rincon
doaj  

Inhibition of p38 MAPK Mitigates Lung Ischemia Reperfusion Injury by Reducing Blood–Air Barrier Hyperpermeability

Frontiers in Pharmacology, 2020
Background: Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process activated by lung transplantation and acute lung injury.
Tiantian Wang, Chunxia Liu, Ling-hui Pan, Zhen Liu, Chang-long Li, Jin-yuan Lin, Yi He, Jing-yuan Xiao, Siyi Wu, Yi Qin, Zhao Li, Fei Lin   +11 more
doaj   +1 more source

Cholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases [PDF]

, 2017
Elevated low-density lipoprotein (LDL) levels induce activation of the p38 mitogen-activated protein kinase (MAPK), a stress-activated protein kinase potentially participating in the development of atherosclerosis.
Dobreva, Iveta, James, Richard W., Waeber, Gérard, Widmann, Christian, Zschörnig, Olaf   +4 more
core  

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways [PDF]

, 2007
Migration and proliferation of smooth muscle cells are key to a number of physiological and pathological processes, including wound healing and the narrowing of the vessel wall.Previous work has shown links between inflammatory stimuli and vascular ...
Agnes Czibula, Andrea R. King, Anthony G. Wilson, Bonventre, Che, Choukroun, David C. Crossman, Du, Emily Heath, Endre Kiss-Toth, Force, Goldschmidt, Grosshans, Hegedus, Hegedus, Hongtao Guan, Hye Youn Sung, Iynedjian, Jones, Ju, Katalin Eder, King, Kiss-Toth, Kiss-Toth, Kiss-Toth, Koo, Lai, Levchenko, Li, Majesky, Mata, McCarthy, Michnick, Mii, Morton, Ohoka, Remy, Remy, Robinson, S. Kim Suvarna, Saka, Sato, Satterthwaite, Schwarzer, Seher, Sheila E. Francis, Stary, Stary, Stary, Steven K. Dower, Surapisitchat, Takeishi, Touyz, Warner, Wilkin, Xia, Yamakawa, Yang, Yue   +58 more
core   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

p38 Mitogen-Activated Protein Kinase Mediates Sidestream Cigarette Smoke-Induced Endothelial Permeability

Journal of Pharmacological Sciences, 2007
Second-hand smoke is associated with increased risk of cardiovascular diseases. So far, little is known about the signaling mechanisms of second-hand smoke-induced vascular dysfunction.
Brad Low, Mei Liang, Jian Fu
doaj   +1 more source

Phosphorylated p38 mitogen-activated kinase in patients with pemphigus vulgaris: a case–controlled study

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background Although the exact pathogenic mechanisms leading to blister formation in pemphigus vulgaris (PV) have not been fully elucidated, intracellular signaling following antibody binding has been found to be necessary for inducing cell-cell ...
Shereen A Sobeih, Marwah A Saleh, Shams M Kholoussi, Eman M El Khateeb, Dina M Kadry   +4 more
doaj   +1 more source