Stimulation of p38 Mitogen-activated Protein Kinase Is an Early Regulatory Event for the Cadmium-induced Apoptosis in Human Promonocytic Cells [PDF]
Alba Galán+6 more
openalex +1 more source
Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar+13 more
wiley +1 more source
p38 Mitogen-activated Protein Kinase Pathway Protects Adult Rat Ventricular Myocytes against β-Adrenergic Receptor-stimulated Apoptosis [PDF]
Catherine Communal+2 more
openalex +1 more source
The Role of Adipokines in Spinal Disease: A Narrative Review
Adipokines, bioactive molecules secreted by adipose tissue, play a key role in both physiological regulation and disease pathogenesis. While their involvement in various organ systems is well documented, their role in spinal pathology remains underexplored.
Jake M. McDonnell+3 more
wiley +1 more source
p38 Mitogen-activated Protein Kinase Regulates a Novel, Caspase-independent Pathway for the Mitochondrial Cytochromec Release in Ultraviolet B Radiation-induced Apoptosis [PDF]
Zerihun Assefa+8 more
openalex +1 more source
Antioxidant Natural Plant Constituents for Diabetic Wound Repair
Antioxidant natural plant constituents promote diabetic wound repair by ameliorating oxidative stress, inhibiting inflammatory responses, and promoting tissue regeneration. ABSTRACT Diabetes mellitus is a prevalent metabolic disorder characterized by a prolonged hyperglycemic state, which can result in complications affecting multiple organ systems ...
Lele Meng+3 more
wiley +1 more source
Role of p38 Mitogen-Activated Protein Kinase in Rhinovirus-Induced Cytokine Production by Bronchial Epithelial Cells [PDF]
Sandra D. Griego+4 more
openalex +1 more source
The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases
Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu+7 more
wiley +1 more source
ABSTRACT Multiple signaling pathways have been implicated in the pathogenesis of ulcerative colitis (UC), including Sphingosine Kinase 1 (SPHK)/Sphingosine‐1‐Phosphate (S1P), AMP‐activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)/NLR family pyrin domain‐containing 3 (NLRP3), zonula occludens‐1 (ZO‐1), and signal transducer and ...
Fatemah A. Alherz+18 more
wiley +1 more source