Results 241 to 250 of about 183,974 (371)

Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases.

Journal of Endocrinology, 2006
R. Reimer
semanticscholar   +1 more source

Structure-Function Studies of p38 Mitogen-activated Protein Kinase [PDF]

Journal of Biological Chemistry, 1997
Yong Jiang, Zhuangjie Li, Edward M. Schwarz, Anning Lin, Kunliang Guan, Richard J. Ulevitch, Jiahuai Han   +6 more
openaire   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway

, 2012
Zhiqiang Zhang, Y Fang, Qiang Wang, Yu Sun, Chuanzhi Xiong, Li Cao, Beiyue Wang, Nirong Bao, Jianning Zhao   +8 more
openalex   +2 more sources

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Mitogen-activated protein kinase phosphatase-2 deletion impairs synaptic plasticity and hippocampal-dependent memory [PDF]

, 2015
Ungless, MA
core   +1 more source

p38 Mitogen-activated Protein Kinase Regulates Interleukin-4-induced Gene Expression by Stimulating STAT6-mediated Transcription [PDF]

, 2002
Marko Pesu, Saara Aittomäki, Kati Takaluoma, Anssi Lagerstedt, Olli Silvennoinen   +4 more
openalex   +1 more source

Ras/Rac-Dependent activation of p38 mitogen-activated protein kinases in smooth muscle cells stimulated by cyclic strain stress

Arteriosclerosis, Thrombosis and Vascular Biology, 2000
Chaohong Li, Yanhua Hu, G. Sturm, Georg Wick, Qingbo Xu   +4 more
semanticscholar   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

A type II collagen peptide activates p38 mitogen-activated protein kinase and its inhibition by hyaluronan via ICAM-1 in articular chondrocytes [PDF]

, 2012
Tsuneo Yasuda
openalex   +1 more source