Results 71 to 80 of about 13,216 (226)

Staying in the Unknown: Avoidance of Genetic Testing in Families With Hereditary Cancer Syndromes—A Qualitative Study

Journal of Clinical Nursing, Volume 35, Issue 12, Page 5694-5708, December 2026.
ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach, Elizabeth E. Half, Hagit Baris‐Feldman, Anastasia Weis, Sharon Simchoni, Sue Kim, Maria C. Katapodi, Sivia Barnoy, Efrat Dagan   +8 more
wiley   +1 more source

P54 Pneumocystis jirovecii prophylaxis in patients on rituximab [PDF]

Rheumatology, 2019
Abstract Background Rituximab is a chimeric monoclonal antibody that depletes the B cell population by targeting cells bearing the CD20 surface marker and is used widely in the management of paediatric rheumatological conditions like juvenile systemic lupus erythematosus (JSLE), juvenile ...
Kishore Warrier1, Catherine Salvesani, Samundeeswari Deepak   +2 more
openaire   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, Volume 13, Issue 62, 9 November 2026.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Multiple binding of repressed mRNAs by the P-body protein Rck/p54

, 2012
International audienceTranslational repression is achieved by protein complexes that typically bind 3' UTR mRNA motifs and interfere with the formation of the cap-dependent initiation complex, resulting in mRNPs with a closed-loop conformation.
Souquere, Sylvie, Le Cam, Eric, Andrey, Philippe, Weil, Dominique, W, Ernoult-Lange, Michèle, Boudier, Thomas, Kress, Michel, Minshall, Nicola, Harper, Maryannick, Baconnais, Sonia, Benard, Marianne, Pierron, Gérard, Weil, Dominique, Standart, Nancy   +13 more
core   +1 more source

P54 Enhancing antibiotic efficacy through nanotechnology: innovations in targeted antimicrobial delivery

JAC-Antimicrobial Resistance
Background Antibiotic resistance poses a growing global health threat, demanding innovative solutions to enhance treatment efficacy.1 Nanotechnology offers promising advancements by enabling precise antibiotic delivery, improving drug stability, and ...
Aser Waleed Mohamed Marzok, Tala Ishola, R. Elshenawy   +2 more
semanticscholar   +1 more source

Immune Regulation by Regnase‐1 and Related Endoribonucleases

European Journal of Immunology, Volume 56, Issue 11, November 2026.
Regnase‐1 couples immune signaling to stem‐loop‐mediated mRNA decay. Its biological output depends on cellular and tissue context, determining whether it restrains inflammation, maintains tissue homeostasis, or suppresses inflammation‐associated tumorigenesis.
Takuya Uehata, Osamu Takeuchi
wiley   +1 more source

The proteomic analysis uncovers the cellular responses to the African swine fever virus membrane proteins p54, p17, and pB117L.

Microbes and infection
African swine fever virus (ASFV) infection causes ASF, a highly contagious and fatal disease that poses severe threat to swine production. To gain insights into the host responses to ASFV, we generated recombinant adenovirus Ad5 expressing viral membrane
Yuhong Chen, Jianqiang Ni, Chuanbin Wang, Xinyan Zhai, Tingrong Luo, Yi-Ping Li, You-Chuan Wei, Yu-Liang Liu   +7 more
semanticscholar   +1 more source

The Impact of Heavy Menstrual Bleeding on Quality of Life: A Mixed‐Methods Survey Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 12, Page 2170-2177, November 2026.
ABSTRACT Objective To examine the physical, psychological, social, and functional impact of heavy menstrual bleeding (HMB) using a mixed‐methods approach. Design Mixed‐methods online survey. Population A UK‐wide sample of adults assigned female at birth with lived experience of HMB.
Michalina Drejza, Lily S. Nicholson, Gabrielle Paquette, Mehar Chawla, Claire L. Vale, Ewelina Rogozińska, Ngawai Moss, Niccola Hutchinson‐Pascal, Bassel H. Al Wattar   +8 more
wiley   +1 more source

Exploring the lived experiences of LGBTQIA+ young people with visible differences: Being ‘double different’

British Journal of Health Psychology, Volume 31, Issue 4, November 2026.
Abstract Objectives Existing research suggests young people with visible differences can experience a range of psychosocial challenges, such as low self‐esteem and increased anxiety and depression. However, young people from minoritised groups are not well represented in visible difference research.
Emma Waite, Elizabeth Jenkinson, Victoria Clarke, Ella Guest   +3 more
wiley   +1 more source

The structural protein p54 is essential for African swine fever virus viability

, 1996
Protein p54, one of the most antigenic structural African swine fever virus (ASFV) proteins, has been localized by immuno-electron microscopy in the replication factories of infected cells, mainly associated with membranes and immature virus particles ...
Escribano, J. M., Rodriguez, José F., García, Ramón, Ley, Victoria, Gómez-Puertas, Paulino, Rodríguez, Fernando, Paulino Gómez-Puertas, Ramón García, Fernando Rodriguez, JoséF. Rodriguez, JoséM. Escribano, Victoria Ley   +11 more
core   +1 more source