Results 211 to 220 of about 101,614 (324)

Regulation of autophagy by oncogene DJ1 via the JNK signaling pathway in human ovarian cancer cells. [PDF]

J Ovarian Res
Zhao XM, Wang K, Wang Z, Xie D, Liu H, Li P, Wang WM.   +6 more
europepmc   +1 more source

Cell Toxicity and Autophagy in A549 Cells Treated With Surface‐Functionalized Graphene Derivatives

Journal of Applied Toxicology, Volume 46, Issue 3, Page 821-832, March 2026.
ABSTRACT Graphene oxide and its derivatives have unique physical and chemical properties with applications in many different fields. However, their biological effects and mechanisms of intracellular toxicity have not been completely clarified. In this study, we investigated the cytotoxic and autophagic activities of graphene oxide and its derivatives ...
Tae Yun Park, Soo Young Kim, Chang Seok Park, Won Young Kim, Jae‐Woo Jung, Jae‐Yeol Kim, Jong Wook Shin   +6 more
wiley   +1 more source

Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo. [PDF]

Nat Commun
Berkamp S, Jungbluth L, Katranidis A, Mostafavi S, Korculanin O, Lu PH, Ickert L, Dierig MM, Sharma L, Thukral L, Huesgen PF, Kononenko NL, Fitter J, Dunin-Borkowski RE, Sachse C.   +14 more
europepmc   +1 more source

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells [PDF]

, 2013
Yu Zhang, J-L Gong, T. Y. Xing, S-P Zheng, Wei Ding   +4 more
openalex   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao, Shuxin Liang, Dingyuan Liu, Xingting Wang, Dan Bai, Chuangjia Huang, Hanliang Sun, Zi Yang, Bitao Wu, Zixuan Chen, Jieyi Feng, Zinan Luo, Jintao Long, Jinsheng Zhu, June Bai, Li Zhang, Aiai Chu, Caojin Zhang, Haiyang Tang   +18 more
wiley   +1 more source

Sequestosome-1/p62 Mediates TLR4-Induced Inflammatory Program in Dendritic Cells Under Normoxic and Hypoxic Conditions. [PDF]

Cell Mol Life Sci
Coppola F, Monaci S, Falsini A, Filippi I, Aldinucci C, Carraro F, Naldini A.   +6 more
europepmc   +1 more source

NS1 binding protein regulates stress granule dynamics and clearance by inhibiting p62 ubiquitination [PDF]

Jin‐A Lee, Pureum Jeon, Hyun-Ji Ham, Haneul Choi, Semin Park, Jae-Woo Jang, Sang-Won Park, Ssang‐Goo Cho, Hyun-Jung Lee, Hyun Kyu Song, Masaaki Komatsu, Deok‐Jin Jang   +11 more
openalex   +1 more source

p62 : A Constitutively Tyrosine-Phosphorylated, GAP-Associated Protein in Chronic Myelogenous Leukemia Progenitor Cells [PDF]

, 1997
Nick Carpino, David Wisniewski, A Strife, Daniel R. Marshak, Ryûji Kobayashi, Bruce Stillman, Bayard D. Clarkson   +6 more
openalex   +1 more source

Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review)

, 2021
Jinlong Tang, Yuan Li, Shuli Xia, Jinfan Li, Qi Yang, Kefeng Ding, Honghe Zhang   +6 more
openalex   +2 more sources

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source