Results 201 to 210 of about 54,852 (260)

RTA-408 induces JNK-dependent apoptosis and autophagy in breast cancer cells. [PDF]

Oncol Lett
Chen YJ, Tsai HP, Chen MY, Chen IH, Chen WC, Tseng TT, Wang CY, Lee JH.   +7 more
europepmc   +1 more source

Recovery From Problematic Gaming Through the Lens of the Transtheoretical Model of Change: A Thematic Synthesis of Forum Posts

Counselling and Psychotherapy Research, Volume 26, Issue 3, September 2026.
ABSTRACT Background With growing concerns over video games being harmful to children and adults alike, research into problematic gaming has been on the rise. While a lot of studies had investigated the effectiveness of different treatment approaches, only a couple of studies explored what the wider process of recovery from problematic gaming looks like.
Ksenija Vasiljeva, Alexandros Kyriakopoulos, Christopher Wilson   +2 more
wiley   +1 more source

Porcine Beclin1 facilitates the proliferation of porcine circovirus type 2 by augmenting autophagy in PK-15 cells. [PDF]

Front Cell Infect Microbiol
Li Y, Wu X, Han J, Geng J, Hu Y, Zhang Y, Song J, Zhang Z, Yang L, Chai J, Li L.   +10 more
europepmc   +1 more source

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

Food Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi, Sally Kamau, Gulnaz Seitimova, Shynar Zhumagaliyeva, Javad Sharifi‐Rad, William N. Setzer, Daniela Calina   +6 more
wiley   +1 more source

Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology. [PDF]

Asian J Pharm Sci
Kim HY, Choi EN, Lee GE, Yoon S, Mun SR, Jung EJ, Kim M, Lim H, Kang YJ, Park WJ, Kwon YT, Park JW.   +11 more
europepmc   +1 more source

Targeting Microglial HDAC3 Enhances Aβ Clearance and Neuroprotection in APP/PS1 Mice: A Ketogenic Diet‐Driven Strategy

Food Frontiers, Volume 7, Issue 5, September 2026.
Ketogenic diet (KD) confers neuroprotection in Alzheimer's disease by inhibiting microglial HDAC3. This simultaneously enhances Aβ clearance via TREM2‐mediated phagocytosis and AMPK–ULK1‐driven autophagy, while suppressing NLRP3 inflammasome activation, ultimately attenuating Aβ/tau pathology and neuronal damage. ABSTRACT Growing evidence suggests that
Mingxiao Zheng, Gabriele Loers, Shengnan Lin, Hans‐Christian Siebert, Qingpeng Wang, Ruiyan Zhang, Xuexing Zheng, Ning Zhang   +7 more
wiley   +1 more source

NRF2 controls a diverse network of antiviral effectors with p62 acting as a central restriction factor effective across virus families. [PDF]

Redox Biol
Pedersen A, Blay-Cadanet J, Storgaard J, Hernaez B, Thyrsted J, Bach-Nielsen CS, Twayana K, Jørgensen SE, Rio-Bergé C, Poulsen C, Thielke AL, Thomsen EA, Kalucka J, Olagnier D, Luo Y, Reggiori F, Mogensen TH, Alcamí A, Hansen AL, Holm CK.   +19 more
europepmc   +1 more source

Fisetin Attenuates Amyloid‐Beta‐Induced Neurotoxicity in Human Neuroblastoma SH‐SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The in‐silico data showed that fisetin binds stably with the autophagy receptors and synaptic density regulators. Further, in‐vitro data confirmed the restoration of Aβ1‐42 disrupted autophagy by fisetin. Fisetin restored the oxidative stress and ion channels, along with a reduction of AChE activity.
Charu Jaiswal, Ishika Singh, Abhishek Kumar Singh   +2 more
wiley   +1 more source

ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein. [PDF]

Virol Sin
Zhao W, Kong N, Lan D, Zhang Y, Liu H, Liu C, Qin W, Yang X, Liu T, Tong W, Yu H, Zheng H, Tong G, Xie S, Xing G, Shan T.   +15 more
europepmc   +1 more source

Post-translational modifications of selective autophagy receptors: orchestrating cellular homeostasis, disease pathogenesis, and therapeutic opportunities. [PDF]

Cell Mol Biol Lett
Zhu W, Wang X, Li Q, Jiang X, Xu G.
europepmc   +1 more source