Results 191 to 200 of about 63,564 (302)

P62 in colorectal cancer: from inflammation suppression to cancer promotion. [PDF]

Front Immunol
A N, Huang J, Liu L, Chen H, Chen J, Zou S, Pang Y, Wu X, Liu M, Liang G.   +9 more
europepmc   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Electroacupuncture Attenuates Cyclophosphamide-Induced Bladder Pain by Restoring Autophagy in Spinal Inhibitory Interneurons. [PDF]

ACS Omega
Xiao Y, Su M, Lai W, Zhou T, Zhu D, Zhao H, Liu B, Wei X.   +7 more
europepmc   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Targeting the senescence‒autophagy axis via p16^INK4a inhibition alleviates pulmonary fibrosis. [PDF]

Signal Transduct Target Ther
Yoo YJ, Zhang M, Jin SH, Lee YR, Jin H, Doan TP, Kim S, Choi S, Park EJ, Na S, Lee Y, Sun J, Cho J, Cho NC, Park SY, Oh WK, Lee YS.   +16 more
europepmc   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, EarlyView.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

The lysine methyltransferase KMT5a and p53 regulate the expression of the key autophagy adaptor p62/SQSTM1 in glioblastoma. [PDF]

Cell Commun Signal
Della Monica R, Buonaiuto M, Cuomo M, Drongitis D, Miano MG, Costabile D, de Riso G, Trio F, Sabbarese M, Ferraro S, Oliva L, Piacentino N, Cappiello R, Scotti G, Lasorsa VA, Capasso M, De Bellis A, Del Basso De Caro M, Chiariotti L, Visconti R.   +19 more
europepmc   +1 more source

Assessing inconsistencies in the FITradeoff method: a comparison of two preference modeling paradigms

International Transactions in Operational Research, EarlyView.
Abstract Many decision‐making processes are susceptible to errors and inconsistencies introduced by decision‐makers (DMs). The development of decision support systems (DSS) has brought about a way to guide DMs through complex decision scenarios. However, due to the complexity of the process, inconsistencies may still arise.
Evanielle Barbosa Ferreira, Lucia Reis Peixoto Roselli, Adiel Teixeira de Almeida   +2 more
wiley   +1 more source

Ubiquitin ligase ITCH regulates life cycle of SARS-CoV-2 virus. [PDF]

Elife
Xiang Q, Wouters C, Chang P, Lu YN, Liu M, Wang H, Heine H, Qian S, Yang J, Pekosz A, Zhang Y, Wang J.   +11 more
europepmc   +1 more source

The GSK3/SHAGGY‐like OsGSK3 phosphorylates and inhibits phase separation of OsFCA at Ser‐43 and Ser‐45 to regulate brassinosteroid signaling and rice architecture

New Phytologist, EarlyView.
A working model for GLYCOGEN SYNTHASE KINASE 3‐mediated phosphorylation of FLOWERING CONTROL LOCUS A in the regulation of brassinosteroid signaling and rice growth and development. Summary Brassinosteroid (BR) signaling plays a critical role in rice (Oryza sativa L.) grain development.
Jiaqi Zhang, Fan Wang, Sijia Zhang, Qian Yu, Qimiao Dong, Jianbo Li, Xianglei Wei, Huaying Du, Ye Shen, Rong Mu, Yanxiao Jia, Jinping Cheng, Hongsheng Zhang, Ji Huang, Xiuying Gao   +14 more
wiley   +1 more source