Results 211 to 220 of about 96,733 (290)

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, Volume 183, Issue 9, Page 1939-1957, May 2026.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Protective role of sodium propionate against glycerol or fractionated doses of gamma rays-induced acute kidney injury via ATF5-induced mitophagy in rats. [PDF]

Sci Rep
Habieb ME, Ali MM, Abd-ElRaouf A, Abdou FY.   +3 more
europepmc   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, Volume 183, Issue 9, Page 1901-1919, May 2026.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

Ift46 deficiency causes renal cyst via enhanced Limk2 through lack of autophagy flux. [PDF]

Cell Commun Signal
Jun JH, Ko JY, Lee EJ, Min J, Choi H, Lee GR, Jung S, Yoo KH, Park JH.   +8 more
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

The interaction of XPG with TFIIH through p62 and XPD is required for the completion of nucleotide excision repair. [PDF]

Nucleic Acids Res
Kim M, Jeong E, Park J, D'Souza A, Tsai MS, Yan C, Ivanov I, Chazin WJ, Kim HS, Schärer OD.   +9 more
europepmc   +1 more source

P62 Sharing website pages to support disease and partner notification: Abstract P62 Table 1 [PDF]

Sexually Transmitted Infections, 2015
openaire   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Correction: A single, acute astragaloside IV therapy protects cardiomyocyte through attenuating superoxide anion-mediated accumulation of autophagosomes in myocardial ischemia-reperfusion injury. [PDF]

Front Pharmacol
Huang KY, Yu YW, Liu S, Zhou YY, Wang JS, Peng YP, Ji KT, Xue YJ.   +7 more
europepmc   +1 more source

B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems, Megan Grace Mazzei, Amanda C. Foks, Coleen A. McNamara   +3 more
wiley   +1 more source