Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle-Activating Capacity. [PDF]
Chen Y +7 more
europepmc +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Recommendations From a Health Care Provider's Perspective for Better Implementation of Telemedicine and Telenursing: Descriptive Qualitative Approach. [PDF]
Hariyati RTS +9 more
europepmc +1 more source
Abstract Objective Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive neuromodulation strategy for drug‐resistant epilepsy, but clinical response is heterogeneous. We examined whether electroencephalographic (EEG) and structural magnetic resonance imaging (MRI) phenotypes were associated with active‐specific clinical benefit from
Sung Jun Hong +6 more
wiley +1 more source
Multiomics reveals alterations in the gut microbiome, host proteins, and host metabolites correlating with SADS-CoV pathogenicity and the immune response in piglets. [PDF]
Tang X +7 more
europepmc +1 more source
ABSTRACT Background Carers are essential in their young person's recovery during transition from child to adult eating disorder services. Despite recommendations, carer's own needs can be overlooked in transition planning. Subsequently, carers experience distress in supporting their young person and navigating the transition.
Isabel Lenham +13 more
wiley +1 more source
A Novel Regulatory System in Brain Development and Death Driven by a Bioactive Peptide Linked to a Specific Isoform of Acetylcholinesterase. [PDF]
Khan AM +4 more
europepmc +1 more source
From Anorexia Nervosa Onset to Treatment Initiation: Experiences of Parents and Young People
ABSTRACT Objective To explore how young people (YP) with anorexia nervosa (AN) and parents experience the period from illness onset to treatment initiation, focussing on perceived impacts on family life. Method An exploratory qualitative study employing 15 interviews with YP (aged 13–17 years) and 20 interviews with parents analysed using reflexive ...
Signe Holm Pedersen +6 more
wiley +1 more source
Emerging applications of Zintl clusters in small molecule activation and catalysis. [PDF]
van IJzendoorn B, Wenger JS, Mehta M.
europepmc +1 more source

