Results 111 to 120 of about 25,950 (247)

Limited effects of preterm birth and the first enteral nutrition on cerebellum morphology and gene expression in piglets [PDF]

, 2016
Preterm pigs show many signs of immaturity that are characteristic of preterm infants. In preterm infants, the cerebellum grows particularly rapid and hypoplasia and cellular lesions are associated with motor dysfunction and cognitive deficits.
Allais, Alvarez-Saavedra, Andersen, Andersen, Ben-Zvi, Blencowe, Brew, Caminita, Cao, Carter, Carter, Chiral, Choudhri, Colvin, Conrad, Dahmane, Dienel, Dobbing, Elmore, Flora, Ghoumari, Gundersen, Gundersen, Haldipur, Haldipur, Hansen, Hart, Hatten, Hou, Hurtado De Mendoza, Jiang, Johnson, Kadomatsu, Keunen, Kiessling, Kieviet, Kim, Kooij, Krigger, Krum, Kuypers, Limperopoulos, Liu, Luissint, Nico, Noguchi, Nosarti, Patra, Radlowski, Rakic, Sadowska, Sangild, Sangild, Sentilhes, Silwedel, Skiold, Skovgaard, Skovgaard, Solowska, Takacs, Vandesompele, Villanueva, Volpe, Volpe, Winter, Wyatt, Yuen   +66 more
core   +2 more sources

THE TrkA RECEPTOR MEDIATES EXPERIMENTAL THERMAL HYPERALGESIA PRODUCED BY NERVE GROWTH FACTOR : modulation by the p75 neurotrophin receptor

Neuroscience, 2016
The p75 neurotrophin receptor (p75NTR) and its activation of the sphingomyelin signaling cascade are essential for mechanical hypersensitivity resulting from locally injected nerve growth factor (NGF). Here the role of the same effectors, and of the TrkA
A. Khodorova, G. Nicol, G. Strichartz
semanticscholar   +1 more source

NRAGE and the cycling side of the neurotrophin receptor p75

Trends in Neurosciences, 2000
Peer ...
openaire   +3 more sources

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

Molecular Microbiology, Volume 125, Issue 3, Page 185-202, March 2026.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç, Robin H. G. A. van den Biggelaar, Tom H. M. Ottenhoff, Leon H. Mei, Anno Saris   +4 more
wiley   +1 more source

Propofol Neurotoxicity Is Mediated by p75 Neurotrophin Receptor Activation [PDF]

Anesthesiology, 2012
Background Propofol exposure to neurons during synaptogenesis results in apoptosis, leading to cognitive dysfunction in adulthood. Previous work from our laboratory showed that isoflurane neurotoxicity occurs through p75 neurotrophin receptor (p75(NTR)) and subsequent cytoskeleton depolymerization.
Matthew L, Pearn, Yue, Hu, Ingrid R, Niesman, Hemal H, Patel, John C, Drummond, David M, Roth, Katerina, Akassoglou, Piyush M, Patel, Brian P, Head   +8 more
openaire   +2 more sources

The link between sarcopenic obesity and Alzheimer's disease: a brain‐derived neurotrophic factor point of view

The Journal of Physiology, Volume 604, Issue 6, Page 2400-2410, 15 March 2026.
Abstract figure legend A, Sarcopenic obesity is defined as the age‐related loss of skeletal muscle mass and function that often leads to the progression of comorbidities, such as Alzheimer's disease (AD). Though the exact link between the two diseases is unknown, alterations in brain‐derived neurotrophic factor (BDNF) may be a contributor.
Emily N. Copeland, Paul J. LeBlanc, Paula Duarte‐Guterman, Val A. Fajardo, Rebecca E. K. MacPherson   +4 more
wiley   +1 more source

Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis.

PLoS Biology, 2011
The neurosteroid dehydroepiandrosterone (DHEA), produced by neurons and glia, affects multiple processes in the brain, including neuronal survival and neurogenesis during development and in aging. We provide evidence that DHEA interacts with pro-survival
Iakovos Lazaridis, Ioannis Charalampopoulos, Vassilia-Ismini Alexaki, Nicolaos Avlonitis, Iosif Pediaditakis, Paschalis Efstathopoulos, Theodora Calogeropoulou, Elias Castanas, Achille Gravanis   +8 more
doaj   +1 more source

Immunohistochemical profile of neurotrophins in human cranial dura mater and meningiomas [PDF]

, 2009
The immunohistochemical profile of neurotrophins and their receptors in the human cranial dura mater was studied by examining certain dural zones in specimens harvested from different regions (frontal, temporal, parietal and occipital).
Alicino, V, Artico, M, Bronzetti, E, D'Ambrosio, A, Elenkov, I, Fumagalli, L, Ionta, B, Pastore, FS, Pompili, E, Santoro, A   +9 more
core   +1 more source

BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis

Frontiers in Pharmacology, 2016
Neurotrophin receptors mediate a plethora of signals affecting neuronal survival. The p75 pan-neurotrophin receptor controls neuronal cell fate after its selective activation by immature and mature isoforms of all neurotrophins.
I. Pediaditakis, A. Kourgiantaki, Kyriakos C. Prousis, C. Potamitis, Kleanthis P. Xanthopoulos, M. Zervou, T. Calogeropoulou, I. Charalampopoulos, A. Gravanis   +8 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source