Results 91 to 100 of about 1,248,941 (203)

Synaptic membrane rafts: traffic lights for local neurotrophin signalling?

Frontiers in Synaptic Neuroscience, 2013
Lipid rafts, cholesterol and lipid rich microdomains, are believed to play important roles as platforms for the partitioning of transmembrane and synaptic proteins involved in synaptic signalling, plasticity and maintenance.
Barbara eZonta, Liliana eMinichiello
doaj   +1 more source

Crystal structure of the neurotrophin-3 and p75 NTR

, 2008
Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine ...
Yong Gong, Yu, H. J., Tao Jiang, Gong, Y., Cao, P., Peng Cao, Jiang, T., Hong-jun Yu   +7 more
core   +1 more source

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

, 2019
The generation of biologically active proteins by regulated intramembrane proteolysis is a highly conserved mechanism in cell signaling. Presenilin-dependent gamma-secretase activity is responsible for the intramembrane proteolysis of selected type I ...
Kim, TW, Murray, S, Kim, DS, Petrova, K, man, N, Ryu, SH, Kim, PK, L, Lewis, R, Chao, MV, Tan, S, Jung, KM   +11 more
core   +1 more source

Activation of NF-kB by nerve growth factor through the neurotrophin receptor p75

, 1996
Carter BD, Kaltschmidt C, Kaltschmidt B, et al. Activation of NF-kB by nerve growth factor through the neurotrophin receptor p75. Science.
Barde, Y. A., Offenhäuser, N., Kaltschmidt, C., Carter, B.D., Kaltschmidt, Christian, Baeuerle, P.A., Kaltschmidt, B., Böhm-Matthaei, R., Baeuerle, P. A., Kaltschmidt, Barbara, Barde, Y.-A., Carter, B. D.   +11 more
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An intracellular domain fragment of the p75 neurotrophin receptor (p75 NTR) enhances tropomyosin receptor kinase A(TrkA) receptor function

, 2013
Facilitation of nerve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neuronal survival and differentiation.
Skeldal, Sune, Sykes, Alex M., Sharma, Aanchal, Palstra, Nickless, Coulson, Elizabeth J., Matusica, Dusan   +5 more
core   +1 more source

Genetically-induced cholinergic hyper-innervation enhances taste learning

Frontiers in Systems Neuroscience, 2011
Acute inhibition of acetylcholine (ACh) has been shown to impair many forms of simple learning, and notably conditioned taste aversion (CTA). The most adhered-to theory that has emerged as a result of this work—that ACh increases a taste’s perceived ...
Selin eNeseliler, Selin eNeseliler, Darshana eNarayanan, Yaihara eFortis-Santiago, Donald B Katz, Susan J. Birren   +5 more
doaj   +1 more source

p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis

, 2009
It is widely acknowledged that neurogenesis occurs in the adult hippocampus under normal conditions and that the rate can be regulated by environmental factors, including antidepressant drugs, with concomitant effects on behaviour.
Al-menhali, Noura, Osborne, Geoffrey W., Bartlett, Perry F., Colditz, Michael J., Coulson, Elizabeth J., Catts, Vibeke S.   +5 more
core   +1 more source

MAG Induces Regulated Intramembrane Proteolysis of the p75 Neurotrophin Receptor to Inhibit Neurite Outgrowth [PDF]

, 2005
SummaryThe three known inhibitors of axonal regeneration present in myelin—MAG, Nogo, and OMgp—all interact with the same receptor complex to effect inhibition via protein kinase C (PKC)-dependent activation of the small GTPase Rho.
Hilaire, M., Chao, M.V., Domeniconi, Marco, Domeniconi, M., Mellado, Wilfredo, Spencer, Tim, Filbin, Marie T., Mellado, W., Zampieri, Niccolò, Zampieri, N., Hilaire, Melissa, Chao, Moses V., Spencer, T., Filbin, M.T.   +13 more
core   +1 more source

The p75 neurotrophin receptor localization in blood-CSF barrier: expression in choroid plexus epithelium

BMC Neuroscience, 2011
Background The presence of neurotrophins and their receptors Trk family has been reported in the choroid plexus. High levels of Nerve Growth Factor (NGF), Neurotrophin-4 (NT-4) and TrkB receptor were detected, while nothing was know about p75 ...
Spuch Carlos, Carro Eva
doaj   +1 more source

The p75 neurotrophin receptor, semaphorins, and sympathetic traffic in the heart

American Journal of Physiology-Heart and Circulatory Physiology, 2010
the sympathetic and parasympathetic branches of the autonomic nervous system control cardiac function through the coordinated activity generated by neurons within the intracardiac autonomic ganglia and central nervous system (3). Activation of the sympathetic efferent projections to the heart increases heart rate, modifies the pattern and conduction ...
Carter BD, Feng N, PAOLOCCI, Nazareno
openaire   +2 more sources