Results 131 to 140 of about 25,950 (247)

Neurotrophic Factor Changes in the Rat Thick Skin following Chronic Constriction Injury of the Sciatic Nerve [PDF]

open access: yes, 2012
Background: Cutaneous peripheral neuropathies have been associated with changes of the sensory fiber innervation in the dermis and epidermis. These changes are mediated in part by the increase in local expression of trophic factors.
Jennifer C Peleshok   +1 more
core   +1 more source

Sphingolipids in Emotional Well‐Being

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Sphingolipids are essential constituents of neuronal membranes and are increasingly recognized as contributors to the key behavioral manifestations associated with emotional well‐being. ABSTRACT Emotional well‐being is a multifactorial concept, which comprises not only life quality of human individuals, but also their mental and physical health.
L. S. Kalinichenko   +4 more
wiley   +1 more source

Synaptic membrane rafts: traffic lights for local neurotrophin signalling?

open access: yesFrontiers in Synaptic Neuroscience, 2013
Lipid rafts, cholesterol and lipid rich microdomains, are believed to play important roles as platforms for the partitioning of transmembrane and synaptic proteins involved in synaptic signalling, plasticity and maintenance.
Barbara eZonta, Liliana eMinichiello
doaj   +1 more source

Observations at the CNS–PNS Border of Ventral Roots Connected to a Neuroma [PDF]

open access: yes, 2010
Previous studies have shown that numerous sprouts originating from a neuroma, after nerve injury in neonatal animals, can invade spinal nerve roots. In this study the border between the central and peripheral nervous system (CNS-PNS border) of ventral ...
Sten Remahl   +4 more
core   +1 more source

Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort [PDF]

open access: yes, 2017
To comprehensively assess whether p75ECD in urine could be a candidate biomarker for ALS evaluation. Urine samples were collected from 101 ALS patients, 108 patients with other neurological disease (OND) and 97 healthy controls.
A Chiò   +26 more
core   +2 more sources

Novel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesis

open access: yesExperimental Neurology, 2015
Human immunodeficiency virus (HIV) rapidly penetrates into the brain and establishes a persistent infection of macrophages/microglia. Activation of these cells by HIV results in the secretion of soluble factors that destabilize neuronal calcium ...
R. Meeker   +4 more
semanticscholar   +1 more source

Involvement of ras p2I in Neurotrophin-induced Response of Sensory, but Not Sympathetic Neurons [PDF]

open access: yes, 1993
Little is known about the signal transduction mechanisms involved in the response to neurotrophins and other neurotrophic factors in neurons, beyond the activation of the tyrosine kinase activity of the neurotrophin receptors belonging to the trk family.
Barde, Y. A.   +4 more
core   +3 more sources

Genetically-induced cholinergic hyper-innervation enhances taste learning

open access: yesFrontiers in Systems Neuroscience, 2011
Acute inhibition of acetylcholine (ACh) has been shown to impair many forms of simple learning, and notably conditioned taste aversion (CTA). The most adhered-to theory that has emerged as a result of this work—that ACh increases a taste’s perceived ...
Selin eNeseliler   +5 more
doaj   +1 more source

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling [PDF]

open access: yes, 2014
International audienceIntroduction: Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels.
Alexis Régent   +15 more
core   +3 more sources

Glioma invasion mediated by the p75 neurotrophin receptor (p75NTR/CD271) requires regulated interaction with PDLIM1

open access: yesOncogene, 2015
The invasive nature of glioblastoma renders them incurable by current therapeutic interventions. Using a novel invasive human glioma model, we previously identified the neurotrophin receptor p75NTR (aka CD271) as a mediator of glioma invasion. Herein, we
B. Ahn   +8 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy