Results 141 to 150 of about 25,950 (247)

Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]

open access: yes, 2012
When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson   +95 more
core   +3 more sources

The p75 neurotrophin receptor localization in blood-CSF barrier: expression in choroid plexus epithelium

open access: yesBMC Neuroscience, 2011
Background The presence of neurotrophins and their receptors Trk family has been reported in the choroid plexus. High levels of Nerve Growth Factor (NGF), Neurotrophin-4 (NT-4) and TrkB receptor were detected, while nothing was know about p75 ...
Spuch Carlos, Carro Eva
doaj   +1 more source

The p75 neurotrophin receptor, semaphorins, and sympathetic traffic in the heart

open access: yesAmerican Journal of Physiology-Heart and Circulatory Physiology, 2010
the sympathetic and parasympathetic branches of the autonomic nervous system control cardiac function through the coordinated activity generated by neurons within the intracardiac autonomic ganglia and central nervous system (3). Activation of the sympathetic efferent projections to the heart increases heart rate, modifies the pattern and conduction ...
Carter BD, Feng N, PAOLOCCI, Nazareno
openaire   +2 more sources

Non-Aβ-dependent factors associated with global cognitive and physical function in alzheimer's disease: a pilot multivariate analysis [PDF]

open access: yes, 2019
Recent literature highlights the importance of identifying factors associated with mild cognitive impairment (MCI) and Alzheimer's Disease (AD).
Di Baldassarre, Angela   +14 more
core   +2 more sources

p75 Neurotrophin Receptor Cleavage by α- and γ-Secretases Is Required for Neurotrophin-mediated Proliferation of Brain Tumor-initiating Cells*

open access: yesJournal of Biological Chemistry, 2014
Background: p75 neurotrophin receptor (p75NTR) is an important mediator of invasion of malignant gliomas, but its role in glioma proliferation is unknown. Results: p75NTR mediates proliferation of brain tumor-initiating cells (BTICs) via its cleavage and
Peter A. Forsyth   +16 more
semanticscholar   +1 more source

Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain [PDF]

open access: yes, 1886
Precursor cells found in the subventricular zone (SVZ) of the adult brain can undergo cell division and migrate long distances before differentiating into mature neurons.
Yoon, Sung Ok   +5 more
core  

A Role for the p75 Neurotrophin Receptor in Axonal Degeneration and Apoptosis Induced by Oxidative Stress*

open access: yesJournal of Biological Chemistry, 2014
Background: The p75 neurotrophin receptor (p75NTR) promotes neurodegeneration during development and in response to cellular injury. Results: Reactive oxygen species promoted cleavage of p75NTR, leading to axonal degeneration and apoptosis.
B. Kraemer   +6 more
semanticscholar   +1 more source

p75 and neural cell adhesion molecule 1 can identify pathologic Schwann cells in peripheral neuropathies

open access: yesAnnals of Clinical and Translational Neurology, 2019
Objective Myelinated Schwann cells (SCs) in adult peripheral nerves dedifferentiate into immature cells in demyelinating neuropathies and Wallerian degeneration.
Young Hee Kim   +15 more
doaj   +1 more source

Neurotrophin Analog ENT-A044 Activates the p75 Neurotrophin Receptor, Regulating Neuronal Survival in a Cell Context-Dependent Manner. [PDF]

open access: yesInt J Mol Sci, 2023
Papadopoulou MA   +7 more
europepmc   +1 more source

Nogo, myelin and axonal regeneration [PDF]

open access: yes, 2005
El sistema nerviós dels mamífers té una baixa capacitat de reparació axonal després d'una lesió. En els últims anys, diversos estudis han demostrat que els axons lesionats no poden recréixer a causa de la presència d'un gran nombre de molècules ...
Mingorance, Ana   +2 more
core  

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