Results 161 to 170 of about 1,248,941 (203)

Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor. [PDF]

Front Cell Neurosci, 2019
Speidell A, Asuni GP, Avdoshina V, Scognamiglio S, Forcelli P, Mocchetti I.   +5 more
europepmc   +1 more source

Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model. [PDF]

Aging (Albany NY), 2019
Mañucat-Tan NB, Shen LL, Bobrovskaya L, Al-Hawwas M, Zhou FH, Wang YJ, Zhou XF.   +6 more
europepmc   +1 more source

Role of p75 neurotrophin receptor in neuronal autophagy in intracerebral hemorrhage in rats through the mTOR signaling pathway.

Cell Cycle, 2020
Wang L, Tian M, Hao Y.
europepmc   +1 more source

Soluble ST2 Is Regulated by p75 Neurotrophin Receptor and Predicts Mortality in Diabetic Patients With Critical Limb Ischemia [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
<b>Objective—</b><p></p> The p75 neurotrophin receptor (p75^NTR) contributes to diabetes mellitus−induced defective postischemic neovascularization.
Marco Meloni, Gaia Spinetti, Orazio Fortunato   +2 more
exaly   +2 more sources

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The p75 neurotrophin receptor and neuronal apoptosis

Progress in Neurobiology, 2000
Although evidence continues to accumulate for the apoptosis-inducing role of the p75 neurotrophin receptor, several outstanding questions remain. One of these concerns the signal transduction pathway of p75, which continues to be elusive. The evidence for the roles of ceramide, c-jun kinase and NF-kappaB is discussed: none of these are able to account ...
Graham L Barrett, G L Barrett
exaly   +3 more sources

Neurotrophin signaling through the p75 neurotrophin receptor

Progress in Neurobiology, 2002
The neurotrophins are growth factors that play critical roles in the development, maintenance, survival, and death of the nervous system. The signal transducing systems that mediate the diverse biological functions of the neurotrophins are initiated by their interactions with two categories of cell surface receptors, the Trk family of tyrosine kinases ...
Philip Barker, Philippe Roux
exaly   +3 more sources

NMR structure of the death domain of the p75 neurotrophin receptor [PDF]

EMBO Journal, 1997
The intracellular domain of the p75 neurotrophin receptor (p75ICD) lacks catalytic activity but contains a motif similar to death domains found in the cytoplasmic regions of members of the tumor necrosis factor receptor family and their downstream targets.
Gottfried Otting, CARLOS Ibanez, Edvards Liepinsh   +2 more
exaly   +3 more sources

Multiple Roles of the p75 Neurotrophin Receptor in the Nervous System [PDF]

Journal of International Medical Research, 2009
The p75 neurotrophin receptor (p75NTR) is a transmembrane protein that binds nerve growth factor (NGF) and has multiple functions in the nervous system where it is expressed widely during the developmental stages of life, although expression decreases dramatically by adulthood.
Ling-Ping Cen
exaly   +3 more sources

Diverse functions of the p75 neurotrophin receptor

Anatomical Science International, 2005
The pan-neurotrophin receptor p75NTR belongs to a large family of receptors, which includes tumor necrosis factor receptors, Fas and approximately 25 other members. The p75NTR is the first receptor to be cloned molecularly. Recent years have seen the emergence of a consensus regarding the signaling pathways activated by p75NTR and its potential ...
Toshihide, Yamashita, Masashi, Fujitani, Katsuhiko, Hata, Fumiaki, Mimura, Satoru, Yamagishi   +4 more
openaire   +2 more sources

The p75 neurotrophin receptor

Journal of Neurobiology, 1994
AbstractThe low‐affinity p75 molecule and trk tyrosine kinases serve as receptors for target‐derived neurotrophins. While the mechanism by which receptor tyrosine kinases impart intracellular signaling has become well understood, the precise roles of the p75 receptor are not fully defined.
openaire   +2 more sources