Results 121 to 130 of about 14,891 (243)

FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis [PDF]

, 2007
After injury, the CNS undergoes an astrocyte stress response characterized by reactive astrocytosis/proliferation, boundary formation, and increased glial fibrillary acidic protein (GFAP) and chondroitin sulfate proteoglycan (CSPG) expression. Previously,
Barnett, S.C., Fairless, R., Frame, M.C., Montague, P., Riddell, J.S., Santos-Silva, A., Smith, G.M., Toft, A.   +7 more
core   +3 more sources

Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats

Journal of Orthopaedic Surgery and Research
Background Fractures heal through a process that involves angiogenesis and osteogenesis but may also lead to non-union or delayed healing. Bone marrow mesenchymal stem cells (BMSCs) have been reported to play a pivotal role in bone formation and vascular
Zhifeng Wu, Yongming Yang, Ming Wang
doaj   +1 more source

Deletion of p75NTR prevents vaso-obliteration and retinal neovascularization via activation of Trk- A receptor in ischemic retinopathy model

Scientific Reports, 2018
Ischemic retinopathy is characterized by ischemia followed by retinal neovascularization (RNV) resulting in visual impairment. Given the role of neuron-secreted growth factors in regulating angiogenesis, we examined how genetic deletion of the ...
Sally L. Elshaer, Azza B. El-Remessy
doaj   +1 more source

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function [PDF]

, 2017
ACKGROUND & AIMS: Hirschsprung disease is caused by failure of enteric neural crest cells (ENCCs) to fully colonize the bowel, leading to bowel obstruction and megacolon. Heterozygous mutations in the coding region of the RET gene cause a severe form of
Garcia-Barcelo, MM, Gui, H, Lai, FPL, Lai, KWH, Lau, CST, Ngan, ESW, Tam, PKH, Tse, HF, Wang, X, Wong, JKL, Zhou, T   +10 more
core   +1 more source

Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling [PDF]

, 2021
Machhindra Garad, Elke Edelmann, Volkmar Leßmann   +2 more
openalex   +1 more source

Expression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumor invasion [PDF]

, 2013
Background: Survivin is detected in few adult normal cells and it is highly expressed in cancer. Nuclear survivin facilitates cell cycle entry, while the mitochondrial pool protects cells from apoptosis.
Dallaglio, Katiuscia, Lotti, Roberta, M., Puviani, Maiorana, Antonino, Marconi, Alessandra, Morandi, Paolo, Petrachi, Tiziana, Pincelli, Carlo, Saltari, Annalisa, Truzzi, Francesca   +9 more
core   +2 more sources

P75NTR+CD64+ neutrophils promote sepsis-induced acute lung injury

Clinical Immunology
Patients suffering from sepsis-induced acute lung injury (ALI) exhibit a high mortality rate, and their prognosis is closely associated with infiltration of neutrophils into the lungs. In this study, we found a significant elevation of CD64+ neutrophils, which highly expressed p75 neurotrophin receptor (p75NTR) in peripheral blood of mice and patients ...
Di, Fu, Shan, Gao, Jia-Nan, Li, Yan-Hui, Cui, Yan-Wei, Luo, Yan-Jun, Zhong, Qiao, Li, Cong, Luo, Ru-Ping, Dai, Ru-Yi, Luo, Zhao-Lan, Hu   +10 more
openaire   +2 more sources

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence [PDF]

, 2015
Ruo Jun Xu, Shikun Duan, Jie Zhao, C.Y. Wang   +3 more
openalex   +1 more source

Editor's evaluation: p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation

, 2022
Moses V. Chao
openalex   +1 more source

p75NTR antibody-conjugated microspheres: an approach to guided tissue regeneration by selective recruitment of endogenous periodontal ligament cells

Frontiers in Bioengineering and Biotechnology
Repairing defects in alveolar bone is essential for regenerating periodontal tissue, but it is a formidable challenge. One promising therapeutic approach involves using a strategy that specifically recruits periodontal ligament cells (PDLCs) with high ...
Xuqiang Zou, Bo Xie, Xuelian Peng, Mingjie Lu, Dan Xu, Hongyan Yuan, Yixin Zhang, Di Wang, Manzhu Zhao, Rui Liu, Xiujie Wen   +10 more
doaj   +1 more source