Investigating the Proteolysis of p75NTR in Response to Oxidative Stress in Dopaminergic Neurons
, 2019 The p75 neurotrophin receptor (p75NTR) is a transmembrane protein receptor with multiple functions including regulating cell survival, neurite outgrowth, and myelination of many distinct populations of neurons.
Clements, Rachel T
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The functions and signaling pathways induced by the interactions of APP–related molecules with p75NTR [PDF]
, 2014 p75 neurotrophin receptor (p75NTR) regulates diverse functions, including survival, differentiation, growth, and apoptosis of neurons, through its association with a number of molecules.
Yuki Fujita, Toshihide Yamashita
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, 2008 Growing evidence has shown that the p75 neurotrophin receptor (p75NTR) may play important roles in controlling neuronal survival or cell apoptosis within the central nervous system in development, and in pathological or neural injury. Recent studies have
Yung, KKL +6 more
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ProNGF BINDING TO p75NTR ACTIVATES PRO-INFLAMMATORY PATHWAYS
, 2017 We recently demonstrated in patients with Juvenile Idiopathic Arthritis (JIA) that a reduced expression of TrkA, the NGF specific receptor, results in decreased anti-inflammatory responses.
Marzia Soligo +6 more
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A p75NTR signaling cascade activates small GTPases to regulate cytoskeletal dynamics
, 2015 The p75 neurotrophin receptor (p75NTR) is a multifunctional receptor that conveys several physiological functions such as cell death and survival, neurite outgrowth, differentiation, and cell migration, and it is also implicated in many pathological ...
Zeinieh, Michele
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The P53 and P75ntr Expression Status in Medulloblastomas: An Insight
<p><strong>Introduction:</strong> Medulloblastomas (MBs) are primitive neuroectodermal tumors (PNETs) located in the cerebellum. They are the most common malignant brain tumors in children, but their origin remains a mystery.
Krushna Chandra Pani +3 more
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Dual-gene regulation of NGF overexpression and P75NTR knockdown enhances BMSC osteogenesis by suppressing pyroptosis. [PDF]
iScienceJi Y +7 more
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The association of p75NTR and co-receptors in hippocampal neurons and astrocytes
, 2015 Neurons in the hippocampus are dependent on neurotrophins for survival. Upon injury, proneurotrophins cause hippocampal neurons to undergo apoptosis. These two distinct effects can be mediated by the interaction of p75NTR with different co-receptors. Trk
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Nerve growth factor receptor (NGFR): A key player in glioblastoma progression. [PDF]
Biochim Biophys Acta Rev CancerKidder BM +3 more
europepmc +1 more source
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity. [PDF]
Adv Sci (Weinh)Rentsendorj A +25 more
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