Results 101 to 110 of about 14,094 (223)

Functional Diversity of Neurotrophin Actions on the Oculomotor System [PDF]

, 2016
Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance of appropriate adult neuronal circuits and phenotypes.
Benítez Temiño, Beatriz, Davis López de Carrizosa, María América, Morcuende Fernández, Sara R., Pastor Loro, Ángel Manuel, Rodríguez de la Cruz, Rosa María, Rodríguez Matarredona, Esperanza   +5 more
core   +1 more source

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

MedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang, Zikai Dong, Yongfei Wang, Ziyi An, Siyuan Wang, Wei‐Lin Jin   +5 more
wiley   +1 more source

Schwann Cell Apoptosis and p75NTR siRNA

Iranian Journal of Allergy, Asthma and Immunology, 2011
The p75 pan-neurotrophin receptor (p75NTR) plays a pivotal role in linking the immune system with the nervous system. p75NTR is required for the development of several characteristic features of allergic asthma.
Masoumeh Firouzi, Farzaneh Sabouni, Abdolkhaleg Deezagi, Zahra Hassannejad Pirbasti, Fatemeh Poorrajab, Vafa Rahimi-Movaghar   +5 more
doaj  

Nerve growth factor improves the muscle regeneration capacity of muscle stem cells in dystrophic muscle. [PDF]

, 2006
Researchers have attempted to use gene- and cell-based therapies to restore dystrophin and alleviate the muscle weakness that results from Duchenne muscular dystrophy (DMD). Our research group has isolated populations of muscle-derived stem cells (MDSCs)
ACOSTA C.G., CLARKE M.S., EVANS C.H., GOROSPE J.R., LYNCH G.S., MANZUR A.Y., PETROF B.J., RUBERTI F., TRIPPEL S.B.   +8 more
core   +1 more source

Sex‐dependent effects of environmental enrichment on mood‐related behaviors, central and peripheral BDNF, and adrenal catecholamine enzymes in mice

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract Housing conditions, particularly environmental enrichment (EE), can influence experimental outcomes and welfare. While EE is generally regarded as beneficial, a male bias exists in research supporting this. This study investigated whether sex differences exist in levels of BDNF in the brain and peripheral tissues in environmentally enriched ...
M. F. Herselman, S. Y. Luo, L. Y. Lin, X. F. Zhou, L. Bobrovskaya   +4 more
wiley   +1 more source

p75NTR receptor – role in cell growth and apoptosis

Postępy Higieny i Medycyny Doświadczalnej, 2012
 The neurotrophins play an important role in the development of the nervous system. These trophic factors affect the cells through the neurotrophin receptors Trk and p75NTR. Trk (tyrosine kinase receptor) mediated signaling promotes survival and growth, while p75NTR-mediated signaling promotes cell death.
openaire   +2 more sources

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Isolation and characterization of neural crest progenitors from adult dorsal root ganglia [PDF]

, 2007
After peripheral nerve injury, the number of sensory neurons in the adult dorsal root ganglia (DRG) is initially reduced but recovers to a normal level several months later. The mechanisms underlying the neuronal recovery after injury are not clear. Here,
Abrous, Ballas, Bedford, Belmadani, Berg, Bixby, Bondurand, Campos, Cecchini, Cheung, Chie, Ciaroni, Corti, Cosgaya, Crane, Devor, Elson, Eng, Evonne Hwee Min Say, Farel, Farel, Farinas, Fernandes, Greenwood, Grothe, Groves, Groves, Groves, Hagedorn, Hong-Yun Li, Hu, Iwashita, Jessen, Kleber, Kruger, Kruger, Kuo, La Forte, Le Douarin, Lee, Lendahl, Lindsay, Lo, Lopez, Ma, Marmigere, Maro, Ming, Mohammed, Molofsky, Mori, Morrison, Murphy, Namaka, Okano, Popken, Pover, Rask-Andersen, Real, Sauka-Spengler, Sommer, Stemple, Steventon, Stewart, Svenningsen, Tomita, Tucker, Valero, Wiggins, Wong, Xian, Xin-Fu Zhou, Yamashita, Yoon, Young, Yun, Zhou, Zhou   +77 more
core   +1 more source

Engram Synapses and Synapse Dynamics in Memory Processing

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Learning‐induced neuronal activity dynamically rewires synapses, altering their formation and elimination rates in task‐related regions. In vivo two‐photon imaging has revealed that activity‐driven presynaptic, postsynaptic, and astrocytic mechanisms regulate synaptogenesis and axonal bouton engulfment.
Yongmin Sung, Chaery Lee, Hyunsu Jung, Bong‐Kiun Kaang   +3 more
wiley   +1 more source

Characterization of NGF, trkANGFR, and p75NTR in Retina of Mice Lacking Reelin Glycoprotein

International Journal of Cell Biology, 2014
Both Reelin and Nerve Growth Factor (NGF) exert crucial roles in retinal development. Retinogenesis is severely impaired in E-reeler mice, a model of Reelin deficiency showing specific Green Fluorescent Protein expression in Rod Bipolar Cells (RBCs ...
Bijorn Omar Balzamino, Filippo Biamonte, Graziana Esposito, Ramona Marino, Francesca Fanelli, Flavio Keller, Alessandra Micera   +6 more
doaj   +1 more source