Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily
Scientific Reports, 2017 The TNFR1-associated death domain protein (TRADD) is an intracellular adaptor protein involved in various signaling pathways, such as antiapoptosis. Its C-terminal death domain (DD) is responsible for binding other DD-containing proteins including the ...
Ning Zhang +3 more
doaj +1 more source
Characterisation of ERK distribution and activity in rat pheochromocytoma cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Biology at Massey University [PDF]
, 1998 Nerve growth factor (NGF) binds to the NGF receptor, TrkA, at the tips of nerve cell axons, sending a signal that prevents programmed cell death and causes survival, growth, and differentiation of the nerve cell.
MacCormick, Matthew Edgar
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Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]
, 2003 Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo +3 more
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proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory cytokines [PDF]
, 2022 Chun‐Rui Yang +13 more
openalex +1 more source
, 2011 My PhD project was aimed at applying microfluidics technology to the study of longrange neurotrophin signalling. Neurotrophins are target-derived growth and survival factors that, among other functions, prevent innervating neurons from undergoing ...
Menendez, Guillermo, Menendez, Guillermo
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NMR Dynamics of Transmembrane and Intracellular Domains of p75NTR in Lipid-Protein Nanodiscs [PDF]
, 2015 Константин С. Минеев +4 more
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Neurotrophins Live or Let Die: Does p75NTR Decide? [PDF]
Neuron, 1997 Carter, Bruce D., Lewin, Gary R.
openaire +2 more sources
Impaired striatal function in Huntington's disease is due to aberrant p75NTR signaling [PDF]
, 2014 Joshua L. Plotkin, D. James Surmeier
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Deletion of p75NTR rescues the synaptic but not the inflammatory status in the brain of a mouse model for Alzheimer’s disease [PDF]
, 2023 Hendrik Demuth +5 more
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Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons [PDF]
, 2019 Huntington\u27s disease (HD) is initially characterized by an inability to suppress unwanted movements, a deficit attributable to impaired synaptic activation of striatal indirect pathway spiny projection neurons (iSPNs).
Carrillo-Reid, Luis +13 more
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