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p75NTR – live or let die

Current Opinion in Neurobiology, 2005
During neuronal development, neurotrophins are essential factors that promote survival, differentiation and myelination of neurons. The trophic signals are relayed to the cells via binding to Trk receptor tyrosine kinases and the p75 neurotrophin receptor.
Anders, Nykjaer   +2 more
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Signalling through the neurotrophin receptor p75NTR

Current Opinion in Neurobiology, 1997
Activation specific tyrosine kinase receptors by neurotrophins accounts for the longest known biological actions of the neurotrophins, in particular the promotion of neuronal survival. However, recent studies have revealed that nerve growth factor, the neurotrophin regarded as best understood, also activates a signalling pathway by binding to the ...
Dechant, G., Barde, Y. A.
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