Results 91 to 100 of about 18,483,123 (229)

Monitoring of nutrient limitation in growing E. coli: A mathematical model of a ppGpp-based biosensor [PDF]

, 2017
Background: E. coli can be used as bacterial cell factories for production of biofuels and other useful compounds. The efficient production of the desired products requires careful monitoring of growth conditions and the optimization of metabolic ...
Pokhilko, Alexandra
core   +3 more sources

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

Journal of Biophotonics, EarlyView.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa, Maria Vitória S. Pereira, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Robust Detection of Hierarchical Communities from Escherichia coli Gene Expression Data [PDF]

, 2012
Determining the functional structure of biological networks is a central goal of systems biology. One approach is to analyze gene expression data to infer a network of gene interactions on the basis of their correlated responses to environmental and ...
A Beyer, AL Barabási, BH Good, BW Kernighan, CO Daub, D Duewer, D Marbach, DFT Veiga, E Bonnet, E Ravasz, E Segal, EH Davidson, F Luo, G Balázsi, G Getz, G Palla, G Palla, H Zare, HW Ma, J Chen, J Duch, J Hubble, J Lemke, J Reichardt, JJ Faith, JJ Faith, JN Weinstein, K Baggerly, Kevin E. Bassler, KY Yeung, M Blatt, M Riley, MB Eisen, MEJ Newman, MEJ Newman, MF Traxler, MM Barker, N Friedman, N Friedman, O Alter, PD Karp, Q Lu, R Guimerà, RA Irizarry, S Fortunato, S Fortunato, S Gama-Castro, S Raychaudhuri, S Tavazoie, Santiago Treviño, Satoru Miyano, SB Seidman, SB Seidman, SP Borgatii, SP Borgatii, TF Cooper, Tim F. Cooper, TS Gardner, U Brandes, UN Raghavan, X Wen, Y Benjamini, Y Sun, Yudong Sun, Z Shi   +64 more
core   +13 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Nucleotide second messengers in bacterial decision making [PDF]

, 2020
Since the initial discovery of bacterial nucleotide second messengers (NSMs), we have made huge progress towards understanding these complex signalling networks. Many NSM networks contain dozens of metabolic enzymes and binding targets, whose activity is
Malone, Jacob, Thompson, Catriona
core   +1 more source

A meet-up of two second messengers: the c-di-AMP receptor DarB controls (p)ppGpp synthesis in Bacillus subtilis

Nature Communications, 2021
Many bacteria use cyclic di-AMP as a second messenger to control potassium and osmotic homeostasis. In Bacillus subtilis, several c-di-AMP binding proteins and RNA molecules have been identified. Most of these targets play a role in controlling potassium
Larissa Krüger, C. Herzberg, Dennis Wicke, Heike Bähre, J. L. Heidemann, A. Dickmanns, Kerstin Schmitt, R. Ficner, J. Stülke   +8 more
semanticscholar   +1 more source

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

Water and Environment Journal, EarlyView.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze, Musa Marimani, Katlego Mamabolo, Mrudula Patel   +3 more
wiley   +1 more source

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence [PDF]

, 2014
Nearly all bacteria exhibit a type of phenotypic growth described as persistence that is thought to underlie antibiotic tolerance and recalcitrant chronic infections.
Behiels, Ester, Devreese, Bart, Elegheert, Jonathan, Félix, Jan, Savvides, Savvas, Vergauwen, Bjorn, Wen, Yurong   +6 more
core   +2 more sources

Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley   +1 more source

The hns Gene of Escherichia coli Is Transcriptionally Down-Regulated by (p)ppGpp

Microorganisms, 2020
Second messenger nucleotides, such as guanosine penta- or tetra-phosphate, commonly referred to as (p)ppGpp, are powerful signaling molecules, used by all bacteria to fine-tune cellular metabolism in response to nutrient availability.
Anna Brandi, Mara Giangrossi, Attilio Fabbretti, Maurizio Falconi   +3 more
doaj   +1 more source